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Vitamin D3 BioSynergy Review – 8 Facts You Need to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | What's Inside? | Health Benefits | Contraindications | Price | Directions | Bottom Line

BioSynergy is a dietary supplement offered by the manufacturer in two versions: the 1000 I.U. soft gels and the 5000 I.U. soft gels. The formula contains a single active ingredient, particularly Vitamin D3.The formula is produced by BioSynergy, a company which was founded in 1994 and is activating in the nutritional supplements industry. All company products are subject to a 30-day money-back guarantee.

Vitamin D3 is believed to have a variety of benefits on the overall health, its most important being in maintaining calcium balance, helping cellular differentiation, enhancing immunity and regulating blood pressure. Vitamin D3 deficiency is associated with loss of memory and mental acuity, weak and/or sore muscles and tender and fragile bones.

BioSynergy is recommended for all the associated disorders which vitamin D3 is used to treat, as the manufacturer does not specifically name the ailment claims for this formula.


1) BioSynergy Quick Facts

BioSynergy is a vitamin based nutritional supplement. The product, in its 2 concentration forms, contains 1000 U.I. or 5000 U.I. of vitamin D3. The vitamin is available in a highly-absorbable liquid soft gel form.

Vitamin D3 plays an essential role in bone and immune system health, as well as some heart and blood vessels conditions. It helps regulate the levels of phosphorus and calcium in the body. Deficiency of Vitamin D3 is related to a large number of disorders and imbalances such as back pain, easy bone fractures, depression, macular degeneration, cancer, pre-eclampsia during pregnancy and insulin resistance.

Vitamin D3 is the only vitamin the body can manufacture from exposure to direct sunlight (UVB). Recent warning about skin cancer caused by sunlight resulted in an increasing number of individuals suffering from vitamin D deficiency.
The manufacturer states that there are no proven side effects of vitamin’s D3 use if taken as directed. Overdose of vitamin D however may lead to fatigue, headache, sleepiness, loss of appetite, and nausea. There are no reviews from consumers regarding this product and no other clinical evidence to support the formula’s effectiveness is provided.

What’s Inside?

2) What’s Inside BioSynergy?

BioSynergy contains the following ingredients: Vitamin D3 (as Cholecalciferol) (from Lanolin), sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish, and preservatives.

3) Is BioSynergy Right for You?

Vitamin D 1000 or 5000 I.U. represents a remedy that normalizes the levels of Vitamin D in the human body. This product contains Vitamin D3. Vitamin D3 deficiency can be targeted by working indoors, avoiding the sun, wearing sunblock, and having dark skin. People who are 60 years old are particularly prone to vitamin D deficiency. Disorders related to Vitamin D deficiency include loss of memory sharpness, sore muscles, weak muscles, fragile bones or brittle bones.

Also, Vitamin D has a role in the maintenance of blood calcium levels within a narrow range which is vital for normal functioning of the nervous system, as well as for bone growth and preserving bone density. Active vitamin D is a potent immune system modulator. Evidence has shown that vitamin D has several different effects on immune system functions and may enhance immunity system while inhibiting the development of autoimmunity.

There are no reported significant side effects regarding the usage within limits of Vitamin D supplements. However, pregnant or lactating women, people with kidney diseases, high levels of calcium in the blood, atherosclerosis, sarcoidosis or histoplasmosis should avoid taking this type of remedies.

Health Benefits

4) BioSynergy Health Benefits

  • Experienced manufacturer
  • Affordable product
  • 30-days refund period if the client is unsatisfied with the product


5) BioSynergy Warnings and Precautions

  • No evidence of clinical testing of the product
  • Contains preservatives and highly allergenic substances (e.g. shellfish, egg and milk)
  • No reviews from consumers to support the formula’s effectiveness


6) BioSynergy Price

Vitamin D is found for purchase at an affordable price, on manufacturer website or some online retailers. It is sold by bottles containing 120 soft gels with the strength of 1000 IU or 5000 IU. The price depends on concentration. Discounts and promotions might be offered.


7) BioSynergy Directions

For optimal blood levels, the suggested dose of BioSynergy is between 2.000 and 8.000 I.U. daily, especially in winter months, taken preferably in the morning with food.

Bottom Line

8) The Bottom Line – “Does it Work?”

BioSynergy is a product advertised as helpful for people who want to improve their overall health and experience the negative effects of Vitamin D deficiency.The manufacturer is an experienced company priding itself with high-quality products from ingredients tested against radiation and of the highest purity.

This is not, however, an FDA approved product and no warnings are made against the use of this supplement in combination with other drugs or by certain people. This is why we believe it is mandatory to consult a healthcare professional whenever you intend to start taking a supplement such as this one.

3/5 - (1 vote)
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Robert Smith

I started using this formula six weeks ago and it has value.