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Thorne Research DL-phenylalanine Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Nutrition Facts | Cost | Does it Work

DL-phenylalanine is promoted as a biological essential amino acid and an important nutrient for a healthy adrenal function that promotes and supports a positive mental state and a healthy stress management. The company behind this product is Thorne Research, the same company behind Thorne Glutathione SR.

According to their website, Thorne Research mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity. They have headquarters in Canada and the USA.

They do not offer a return policy for DL-phenylalanine. However, the company offers multiple ways to contact them. Consumers can communicate with the Customer Support service via email, phone or contact form.

Nutrition Facts

1) DL-phenylalanine Nutrition Facts

DL-phenylalanine includes the following ingredients: DL-Phenylalanine and Hypromellose (derived from cellulose) capsule.

2) Does DL-phenylalanine Work?

DL-phenylalanine is an essential amino acid that can be found naturally in the breast milk of mammals. DL-Phenylalanine (DLPA) is marketed as a nutritional supplement for its supposed analgesic and antidepressant activities. Clinical studies have shown that this amino acid inhibits endorphin degradation, which leads to an inhibition of GABA release. Increased GABA levels will eventually lead to a greater dopamine release, which can explain the analgesic effects of DLPA the following ingestion.

Although the manufacturer claims that its formula promotes a positive mental state and a healthy stress management, there is no information at all that supports these claims. It is dangerous to create bold claims of this nature without providing some detailed information about how the product. In fact, the official website (and the product’s page) lacks relevant information.

The official website lacks customer’s testimonials. However, based on our research, reviews and testimonials regarding this product are rather mixed. Some people report positive results while others report no results at all.

The daily recommended dose of this amino acid varies based on the type of supplementation that a consumer it is using. Typically it has to be taken once or twice a day before a meal. It is important to carefully read all of the instructions on such products so that the recommended dose isn’t exceeded.


3) DL-phenylalanine Cost

DL-phenylalanine price per capsule is what makes it of an overall good value. A bottle usually contains 60 capsules, which should be enough for one month of treatment to the average user. Compared to similar products, DL-phenylalanine can be considered inexpensive.

This supplement can be purchased directly from the manufacturer’s website or various online retailers. Shipping costs are determined based on location. However, some retailers may offer additional discounts and even free shipping for larger purchases.

Does it Work

4) Bottom Line – Does It Really Work?

Though Thorne Research is a relatively unknown name for some, the company has been getting some positive reviews and testimonials. While this is a good thing, the lack of testimonials on the official website is curious, to say the least.

DL-phenylalanine is a well-known ingredient that has shown to be effective during several clinical trials and researches. However, while we do have some information on the ingredients, the Effectiveness of their overall formula has never been proven. Thus, we recommend our readers to focus on products that have been fully researched and proven to work.

4/5 - (1 vote)
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