Home » Reviews » Nootropics » Smart Pill Review

Smart Pill Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Nutrition Facts | Claims | Contraindications | Cost | Directions | Verdict

Smart Pill is a brain supplement designed to support brain function and to promote overall health. Particularly, the manufacturer Only Natural advertises as specific product benefits improved memory, concentration and attention span and increased mental alertness.

Only Natural is a company set up in 1986 which specializes in manufacturing and marketing vitamins and natural supplements. The company claims all products are accompanied by a Certificate of Analysis to guarantee that each product is of the highest quality and supports the supplemental facts listed on the label. Additionally, supplements use ingredients that are kosher, organic, gluten-free and vegetarian and are manufactured under NPA’s Good Manufacturing Practices (GMP) guidelines.

Smart Pill is recommended to adults who seek to enhance their mental performance and to support a good general health.


1) What is Smart Pill?

Smart Pill is a blend of herbal extracts, vitamins, amino-acids and co-factors designed to improve mental alertness, memory and concentration, similar to popular nootropics like Qualia Mind.

The formula features a standardized extract of Ginkgo Biloba which has been used in clinical studies and is proven safe and effective. Ginkgo Biloba has powerful antioxidant properties, helping fight free radical damage. This is why numerous clinical trials and research is currently conducted to prove its potential benefits in preventing and treating conditions that impair brain function and are caused by free radical damage.

Also Ginkgo is known as a blood flow enhancer, ensuring optimum delivery of nutrients and oxygen to the brain and hence contributing to maintaining good cognitive function. Its benefits on memory and mental clarity are backed up by actual scientific evidence. Ginkgo is considered safe but has been reported to cause stomach upset, nausea, dizziness, diarrhea or headache. Concern exists on how it may interact with blood thinning medication, hence caution is advised.

Preliminary research supports Korean Ginseng’s medicinal uses in several areas. It appears to be an effective treatment in erectile dysfunction, lowering blood pressure and bone healing. One of its most important benefits is the capacity to improve mental clarity and function. Scientists believe that when combined with Gingko Biloba it can also help to enhance memory. Side effects include digestive problems, headaches, sleep disturbances, restlessness and anxiety. Precaution is recommended for people taking MAO inhibitors or when taking caffeine.

Nutrition Facts

2) Smart Pill Nutrition Facts

Smart Pill includes the following ingredients: Ginkgo Biloba leaf extract 10:1, Gotu Kola, Ginseng, Capsicum (Cayenne), L-Phenilalanine, L-Glutamine, L-Tyrosine, GABA, Vitamin B1, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B12, Folic Acid, Inositol, Phosphatidylcholine as Lecithin, RNA, and TMG.

3) Does Smart Pill Work?

Smart Pill is a dietary supplement that blends vitamins, amino acids, and herbal extracts to sustain mental alertness, memory and concentration. One of the ingredients used in this formula is Vitamin B-1, also known as Thiamine, which sustains almost all functions present in the body, but plays a key role in brain health and function. A deficiency of this vitamin can lead to several neurological function problems. The most common use of Thiamine is to improve brain function; it acts as a neurotransmitter helping the brain prevent learning and memory disorders; it also provides help with mood disorders and offers stress relief.

Another ingredient used in this formula is GABA or Gamma-Aminobutyric acid; it’s the second most common neurotransmitter found in the human brain. Being an inhibitory neurotransmitter it helps calm and reduce neuronal activity; this calming effect makes GABA an excellent ingredient in anti-anxiety medication. Lecithin is another ingredient found in Smart Pill and is a basic compound found in every cell of the body, with cardiovascular benefits it can also help restore the liver. Another effect is that it works with neurological functions such as memory or attention, thus improving brain Effectiveness.

This formula can be bought in the form of a bottle that contains 30 or 60 tablets, no sugar yeast or starch is found in this blend, as well as no coffee. This compound might cause a warm flushing of the skin, an effect that is harmless and can be relieved by drinking a cup of water.


4) Smart Pill Claims

  • The formula uses a standardized extract of Ginkgo Biloba, which is used in clinical research and is proven safe and effective
  • Moderate price (approx. $18 for a month’s supply)
  • Contains a number of essential vitamins which support key body functions and structures

5) Smart Pill Warnings and Precautions

  • Side effects and special precautions associated to some of the herbal ingredients
  • Mixed consumer reviews
  • The daily dosages for many ingredients have not been established

6) How Much Does Smart Pill Cost?

This formula presents a relatively high price and one bottle of 60 tables, at the recommended dosage of two tablets per day with a meal, a bottle provides a month’s supply. The secure online purchase is available on the manufacturer’s site as well as at several online retailers. Although no free trials or money back guarantees are available at this time, the manufacturer provides free shipping if the desired order exceeds a certain amount. With time different online retailers could offer some advantages depending on the amount purchased, so an online research is advised before purchase, as to assess the market and find the best solution.


7) Directions For Taking Smart Pill

The manufacturer recommends taking 2 tablets of Smart Pill daily. No side effects or special precautions are mentioned. Consumer reviews are limited in number and report mixed results.


8) Our Verdict on Smart Pill

In a combination of vitamins, herbs, amino acids and co-factors, Smart Pill promises to provide support for brain function and overall health. The brain health benefits include memory, concentration and alertness. They are justified by the manufacturer through the use of ingredients which have been studied and proven effective on brain health and performance. Particularly, ingredients such as Ginkgo Biloba, Gotu Kola, Siberian Ginseng, GABA or Phospahtidylcholine positively impact brain function through various different mechanisms.

The formula also features a wide range of vitamins, hence the claim that it can benefit the overall body health. Smart Pill has received mixed reviews, some consumers saying they are satisfied and see results, while others mention the slow, unsatisfying action of the supplement.

However, you should remember that each person is different and you can increase the probability of choosing the right formula for you if you first consult a healthcare specialist.

4.5/5 - (2 votes)
Notify of
Inline Feedbacks
View all comments

I had used this for 15+ years and it works! It is hard to find right now and I am not sure if the company has discontinued it. Anyone know?

Title for your comment
It works!
Have you tried this product?
Verna H. Maziarz

My attention is better now thanks to this formula, I can now manage school with ease.