Home » Reviews » Vitamins » Flush-Free Niacin Review

Flush-Free Niacin Review – 8 Facts You Need to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | Ingredients | Claims | Precautions | Cost | How To Use | Bottom Line

Flush-Free Niacin is a vitamin supplement manufactured under the brand name Nature Made. This product is design to promote circulatory health, while removing the common side effect that Niacin usually has flushing. This supplements aim to replace classic B3 vitamins, that have the same effects as this product, but the downside of sometime causing skin coloring and mild spotting.

Nature Made, a brand of Pharmavita, has earned the reputation of developing high quality products, which has earned them a large amount of customers. They also earned numerous awards and certificates that attest to the large amounts of focus place in providing quality products. Unlike other pharmaceutical companies, they also strive to keep their prices accessible for their customers.


1) Flush-Free Niacin Quick Facts

Flush-Free Niacin is a vitamin-based formulation that is supposed to help with blood vessel and circulatory health.

The type of Niacin found in this supplement is Inositol Hexanicotinate, an esterified variant of vitamin B3. While this substance is, indeed, proven to not cause the same flushing effect as active niacin, it seems it has little medical use. Due to the lack of free nicotinic acid there are no evident positive effects on health, but there might be negative effects on liver enzymes, requiring monitoring during periods of regular Inositol hexanicotinate intake.


2) Details on Flush-Free Niacin Ingredients and Uses

Flush-Free Niacin contains: Inositol Hexanicotinate, Soybean Oil, Gelatin, Glycerin, Water, Soy Lecithin, Yellow Beeswax, and artificial colors (Titanium Dioxide, Copper Chlorophyllin).

3) Does Flush-Free Niacin Work?

Flush-Free Niacin is advertised to be a flush-free niacin product which is appropriate for general circulatory health. Because of this, it may not provide the same type of benefits as a regular niacin supplement.

The first thing you need to understand about this product is the fact that it is based on inositol hexanicotinate, which differs from nicotinic acid, the most common form of niacin. Even though this type is said to be flush-free, it may not be as potent as nicotinic acid. Being a part of the B vitamins, Niacin helps the body in the conversion of food (carbohydrates) into glucose (the fuel used to produce energy), while aiding in the metabolism of fats and protein. It is a water-soluble vitamin, which means it must be continuously obtained from the diet as the body cannot store it. However, niacin deficiency is very rare. Anyone in the developed world should meet all of his body’s needs for vitamin B3 through the diet.

This compound is included in dietary supplements for the purpose of supporting the cardiovascular system. Some studies suggested that supplementation with niacin alone seemed to reduce the risk of heart attack or stroke. Combined with colestipol, vitamin B3 may slow down the progression of atherosclerosis, lowering the risk of heart attacks. Niacin was also shown to reduce cholesterol levels in some individuals.

The suggested daily dose is one soft gel capsule, with a meal. You should not take niacin along with anti-diabetic drugs, anticoagulant and anti-platelet drugs, and statin drugs.


4) What Flush-Free Niacin Does?

  • Inexpensive product, a bottle can last up to two months and costs $7
  • Manufacturer offers a money-back guarantee for all their products
  • Shipping costs vary depending on retailer, but are, on average, lower than $6
  • Active ingredient medically proven not to cause flushing


5) Precautions of Flush-Free Niacin Use

  • Medical evidence suggests that this form of niacin is ineffective
  • Product contains artificial colors
  • Purchasing directly from the manufacturer is not possible
  • Caution advised if taking prescription medication with this supplement


6) How Much Does Flush-Free Niacin Cost?

Flush-Free Niacin is average-priced. It is available in sizes of 60 or 200 soft gel capsules. The larger container has a far better value.

You can purchase this supplement from various sources, online or offline. You should compare prices before making a purchase as some retailers may be offering discounts or money-back guarantees. Unfortunately, the manufacturer does not sell this product directly.

How To Use

7) How to Use Flush-Free Niacin

If you are taking prescription medication, it is advised you consult your doctor before using this product. It is particularly recommended if you are taking anti-diabetic, anti-coagulant, anti-platelet or statin drugs. This supplement is not recommended for pregnant or nursing women. The daily suggested dose is one capsule, taken with a meal.

Bottom Line

8) Our Bottom Line

Many people want to ensure their circulatory system is kept healthy, particularly seeing as it is among the first elements of the body to suffer from an inadequate lifestyle. However, the side effects associated with consumption of normal Niacin supplements lead people to turn towards products like Flush-Free Niacin that remove the flushing effect. Unfortunately it seems that removing the flushing effect also reduces the medical effect, possibly rendering such problems useful.

There is a possibility that Nature Made’s claims are valid, as suggested by reports coming in from customers, all of which state that Flush-Free Niacin performed as advertised and that they are very happy with the supplement.

4/5 - (1 vote)
Notify of
Inline Feedbacks
View all comments