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AnxiousLess Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | Ingredients | Health Benefits | Side Effects | Cost | Where to Buy? | How To Take | Bottom Line

Nature’s Sunshine’s AnxiousLess is a dietary supplement designed to relieve stress and anxiety and improve sleep quality through its unique proprietary blend of herbs and vitamins, including Sceletium tortuosum, Vitamin B1, Magnesium, and L-Theanine.

The formula is designed to help relieve the nervousness, tension, and worry associated with daily living.

Our AnxiousLess review below analyzes this multimineral supplement’s most critical elements, beginning with its manufacturer, and will discuss its claimed benefits, potential side effects, cost per serving, and what consumers think of the product.

If you’d like to find out more about AnxiousLess and how you or a loved one can benefit from taking it, keep reading this article.


1) AnxiousLess Quick Facts

AnxiousLess is made by Nature’s Sunshine, an American MLM company headquartered in Lehi, Utah.

Unlike some anxiety relief products, AnxiousLess is made with all-natural ingredients to ensure product safety and customer comfort as they know exactly what goes into their bodies.

The supplement is advertised as an excellent option for occasional anxiety relief, positive mood, and more energy throughout the day.

Furthermore, Nature’s Sunshine claims the product is 100% safe, non-habit forming (non-addictive), and doesn’t cause drowsiness.

2) The Company Behind AnxiousLess

Nature’s Sunshine is an MLM company (Multi-Level Marketer) founded in 1972 by Gene and Kristine Hughes[1].

As an MLM, the company works primarily through independent distributors to increase accessibility to its products and supplements.

Today, Nature’s Sunshine makes a wide range of dietary supplements, including multivitamins, herbs, minerals, and personal care products.

Some of its best-selling supplements include Nutri-Calm, Chlorophyll Liquid ES, Stress-J, Mind-Max, AnxiousLess, and HistaBlock.

You can contact Nature’s Sunshine via the following options:

  • Address: 2901 W Blue Grass Blvd., Lehi, UT 84043
  • Phone: 1 (800) 223-8225 Monday-Friday: 6:00 AM to 6:30 PM MST
  • Website: naturessunshine.com

3) Details on AnxiousLess Ingredients and Uses

AnxiousLess contains the following active ingredients:

  • Thiamin (Vitamin B1, mononitrate) 5 mg
  • Magnesium (citrate) 40 mg
  • Zinc (gluconate) 1 mg
  • Proprietary Blend [L-Theanine, Zembrin (Sceletium Tortuosum aerial parts)] 75 mg

Thiamine (Vitamin B1) is an essential nutrient for every cell in the body and a cofactor for enzymatic reactions in the heart, brain, skeletal muscles, liver, and kidney[2][3].

Naturally, Vitamin B1 is found in many foods, including yeast, cereal grains, beans, nuts, and meat.

Like other B-complex vitamins, Vitamin B1 is often depicted as an “anti-stress” vitamin because it can improve the body’s capacity to endure stressful conditions and strengthen the immune system[4].

Thiamine helps convert carbohydrates into glucose[5], the favored energy source that the body runs off to keep your metabolism running smoothly. It also helps break down fats and proteins.

Vitamin B1 is also vital for a system of enzymatic reactions involving pyruvate dehydrogenase[6], which works to metabolize the sugars that we eat.

Magnesium is involved in over 600 cellular reactions[7], including the nervous system’s functioning, muscle function, activation of B vitamins, and muscle relaxation. It plays an essential role in neuromuscular transmission and activity.

Magnesium is also used in nutritional supplements to support heart health, lower blood pressure, improve sleep quality, help combat migraines, and help reduce symptoms of depression[10][11][12][13][14].

Common sources of Magnesium include:

  • Cashews
  • Pumpkin seeds
  • Beet greens
  • Swiss chard
  • Black beans
  • Spinach
  • Flaxseeds
  • Dark chocolate
  • Almonds
  • Salmon
  • Avocado
  • Tofu

L-Theanine is a vital amino acid believed to improve mood, enhance focus, and improve concentration. Commonly found in tea, L-Theanine is one of the amino acids that can cross the blood-brain barrier (BBB)[15].

L-Theanine has unique psychoactive properties because it can affect numerous biochemical pathways. It has been discovered[16] to reduce mental and physical stress and produce feelings of relaxation. It may also improve cognition and mood.

Researchers consider that L-Theanine can produce these effects by increasing GABA, dopamine, and serotonin levels in the brain[17]. L-Theanine also promotes alpha wave production in the brain, which helps people feel relaxed and positive.

Zembrin, a patented form of the native South African plant, Sceletium tortuosum boosts Serotonin levels by preventing its reuptake, a feature shared by a class of antidepressant medications known as (Selective Serotonin Reuptake Inhibitors, SSRIs.

Serotonin is a known mood stabilizer that also regulates sleep, sexual desire, and digestion.

Other ingredients in AnxiousLess include cellulose, gelatin, water, and vegetable magnesium stearate.

Health Benefits

4) AnxiousLess Health Benefits

Some of AnxiousLess’ claimed benefits include:

  • Ideal for occasional stress, anxiousness, tension, and anxiety relief
  • Provides mood support without any crashes or drop in energy level
  • Helps promote calm and improved focus
  • Elevates mood
  • Improves sleep quality
Side Effects

5) AnxiousLess Side Effects

Given the ingredients available in this multimineral supplement, some people may experience mild adverse effects. These are usually a response to how their bodies adjust to the supplement and are often short-lived.

Some of these effects[18][19][20] may include:

  • Irritability
  • Constipation
  • Vomiting
  • Headaches
  • Sweating
  • Restlessness
Where to Buy?

6) Where to Buy AnxiousLess

You can purchase AnxiousLess from the official Nature’s Sunshine store or select online retailers like Amazon.


7) How Much Does AnxiousLess Cost?

One bottle of AnxiousLess (30 capsules / 30 servings) costs $41.95. The supplement is also available in bottles of 90 capsules each for $90.35, with discounts available on larger purchases.

If you’re looking to complement AnxiousLess, check out our C247 Food Supplement review.

How To Take

8) How to Take AnxiousLess

As a dietary supplement, take one (1) capsule daily as needed.

9) What Users Are Saying

"It did not work on me at all. I didn't feel any different, took for a couple of days. These are too expensive not to work." [Read full review]

---Jasmine V. Dsouza

"I have taken Nature Sunshine Herbs for most of my life. My mom used to be a distributor, so I know a lot about Nature Sunshine. I trust this company. I also know that you have to take herbs for longer than just a few days or months to get the benefits. I have been taking this Nature Sunshine's AnxiousLess for a while now, and it just didn't work for me. So I'm going to try another one for my anxiety." [Read full review]


"Both my son and I like this product. It was initially recommended by a Christian Counselor, which I no longer see. But, I have taken her recommendation to try/use the product. I find it very helpful in relaxing and sleeping." [Read full review]


Bottom Line

10) The Bottom Line – “Does it Work?”

Although AnxiousLess may be a pricier dietary supplement of this type, its main ingredient, Sceletium tortuosum, is science-backed and proven to effectively boost serotonin levels in the brain, relieving anxiety and depression in the process.

Overall, AnxiousLess may be a good option for those looking for a natural supplement for occasional stress, anxiousness, tension, and anxiety relief.

However, users should note that AnxiousLess is not intended to diagnose or cure any medical illnesses and should only be used as recommended.

3.7/5 - (3 votes)

Reference Sources

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