Home » Reviews » Other » AZOTH Total Focus Review

Total Focus Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Ingredients | Health Benefits | Side Effects | Warnings | Cost | Where to Buy? | How To Take | Bottom Line

AZOTH Total Focus is advertised as a potent nootropic supplement for “extreme focus, attention, and concentration.”

The key feature of this brain supplement is Zynamite at 200 mg per serving, a patented proprietary mango leaf extract introduced back in May of 2018.

According to AZOTH, Zynamite has been proven to deliver an impressive variety of benefits, including improved energy, alertness, and performance, all without jittery side effects typically associated with the use of stimulants.


1) What is Total Focus?

Zynamite is an award-winning, patented proprietary Mangifera indica extract. Infusions and decoctions of mango leaves are used extensively in traditional health systems for their multiple benefits.

Research suggests that Zynamite may improve reaction time, increase mental performance, increase focus & attention, improve energy, accelerate recovery, reduce pain & muscle damage, and increase power during exercises.

Before moving on with our AZOTH Total Focus review, let’s see what science says about this patented nootropic ingredient:

  • A 2019 randomized controlled trial[1] published in Nutrients analyzed the potential benefits of supplementing with Mangiferin and Luteolin extracts to improve exercise performance in men. The scientists concluded that acute and prolonged supplementation with Mangiferin combined with Luteolin enhances performance, muscle oxygen extraction, and brain oxygenation during sprint exercise at high and low doses.
  • In a 2018 study[2] published in Frontiers in Psysiology, researchers observed the benefits of a Mangifera indica extract in combination with Luteolin or Quercetin. The volunteers received either a placebo or a Zynamite-rich Mangifera indica L. leaf extract. Those who received the Zynamite-rich extract had better sprint performances and recovery from ischemia-reperfusion.

2) The Company Behind Total Focus

Total Focus is made by AZOTH LLC, an American company founded by Prady Tewarie in August 2017.

The company has had success with an aggressive marketing strategy claiming to produce some of the “strongest nootropics on the market.” Despite its over-the-top claims, the sales have been skyrocketing; AZOTH LLC is currently selling products in over 38 countries.

Some popular nootropic supplements from this company include:

  • Total Focus
  • Total Memory
  • AZOTH 3.0 Total Brain
  • Pure Energy Zynamite

How to contact AZOTH company:

  • Address: 1 Franklin St, Suite 1609, Boston, MA 02110
  • Website: getazoth.com
  • Phone: +1-617-213-0478

3) Total Focus Ingredients

AZOTH Total Focus contains the following active ingredients:

  • C3X Complex [Caffeine anhydrous, Methylliberine (as Dynamine), and Theacrine (as TeaCrine)] 300 mg
  • Zynamite [Mangifera Indica extract (Mango leaf extract standardized to >60% Mangiferin)] 200 mg

Other inactive ingredients include rice flour, magnesium stearate, and vegetable capsule (microcrystalline cellulose).

4) Does Total Focus Work?

AZOTH Total Focus’ formula contains two active proprietary blends: 300 mg of C3X Complex and 200 mg of Zynamite.

Let’s start by discussing the C3X Complex first.

Caffeine is a chemical found in approximately 50 different plant species humans have consumed for thousands of years. You’re probably aware of typical plants caffeine sources, such as coffee, green tea, and dark chocolate (cacao).

Caffeine anhydrous is obtained from these plants following a chemical process. During this process, all other components of the plants, along with any water, are removed. The result is a white crystalline powder called caffeine anhydrous (anhydrous means “without water”)[3].

The most popular forms of caffeine anhydrous are powders and pills. However, the FDA recommends[4] avoiding any pure powders. There is a fine line between a safe and unsafe dose, and a small mistake in measurement could result in dangerous adverse effects.

Caffeine anhydrous works in a similar way to caffeine. It’s a sneaky impersonator of another chemical in your brain – a neurotransmitter called adenosine. When adenosine locks on to specific receptors in the brain, it makes you slow down and feel sleepy[5][6][7].

More “scientifically” known as Methylliberine (or tetramethyluric acid), Dynamine is a brand-new stimulant – and, according to some reports, nootropic – supplement that has recently appeared on the market. While most of you have probably never heard of Dynamine (or Methylliberine), it is claimed to offer a long list of advantages.

According to the supplement manufacturers promoting Dynamine, this new stimulant nootropic comes with an incredible array of benefits.

The benefits[8][9] said to be associated with the use of Dynamine include:

  • Enhanced energy, mood, and focus
  • A rapid increase in mental and physical energy
  • Decreases fatigue
  • Faster acting than Ttheacrine

The main benefit of Dynamine seems to be that it is much faster acting than other stimulants such as Theacrine while also being much shorter in duration. This makes it ideal for people who need a quick energy and focus boost but who do not want to be kept up all night as they might be with caffeine.

Theacrine is a naturally occurring chemical that is similar to caffeine. It is found in different types of tea and coffee and in the seeds of the Herrania and Theocrama plant species. It is also found in the tea plant Camellia assamica traditionally used to prolong life and cure the common cold.

Preclinical and human clinical research shows[10][11][12][13] TeaCrine® facilitates a wide range of healthy functions while providing an edge in the fiercely competitive and rapidly growing markets of energy, performance, and cognitive achievement. Yet, it’s not a stimulant, and it provides energy without the jitters or crashes.

Zynamite is advertised as a multi-award-winning patented botanical extract that provides benefits beyond those of caffeine.

As a natural and sustainable alternative to caffeine, the premium botanical ingredient has been clinically documented to provide a significant, sustained mental and physical performance boost.

Studies[14][15] have shown that Zynamite activates brain waves in almost identical patterns to caffeine, but using a different mechanism doesn’t cause any of the side effects of caffeine.

While Total Focus is definitely a stimulating nootropic, some users prefer a more stim-free approach to their nootropics. This is particularly important if they already have an alternative caffeine source or if they simply don’t like the “buzz” or side effects associated with caffeine use.

If you prefer a stim-free alternative to Total Focus, give our Brainol Review a read and see if it’s a nootropic you’d like.

Health Benefits

5) Total Focus Health Benefits

AZOTH Total Focus claimed benefits include:

  • Improves focus, concentration, and attention
  • Proven to work in over 25 human trials and studies
  • The world’s only nootropic supplement that contains Zynamite and C3X Complex
  • Safe to use with no potentially dangerous adverse effects
Side Effects

6) Total Focus Side Effects

AZOTH Total Focus is advertised as a safe-to-use nootropic supplement. However, the formula contains caffeine, which may cause mild to moderate adverse effects in persons sensitive to caffeine and stimulants.

Some AZOTH Total Focus side effects[16][17] may include:

  • Headaches
  • Insomnia
  • Dehydration
  • Dizziness
  • Restlessness and shakiness
  • Rapid or abnormal heart rhythm
  • Anxiety

7) Total Focus Product Warnings

As with all dietary supplements, we recommend caution when taking AZOTH Total Focus if under treatment with prescription medication.

Given the ingredients in AZOTH Total Focus, the nootropic may interact[18][19] with certain prescriptions, including but limited to:

  • Stimulant drugs (like Ephedrine)
  • Antibiotics [like Enoxacin (Penetrex), Ciprofloxacin (Cipro), Sparfloxacin (Zagam), Trovafloxacin (Trovan), Norfloxacin (Chibroxin, Noroxin), and Grepafloxacin (Raxar)]
  • Estrogens [like conjugated equine estrogens (Premarin), Estradiol, and Ethinyl Estradiol]
  • Fluvoxamine (Luvox)
  • Lithium
  • Medications that slow blood clotting [like Diclofenac (Voltaren, Cataflam), Clopidogrel (Plavix), Ibuprofen (Advil, Motrin), Dalteparin (Fragmin), Naproxen (Anaprox, Naprosyn), Heparin, Warfarin (Coumadin), Enoxaparin (Lovenox)]
  • Medications for depression
Where to Buy?

8) Where to Buy Total Focus

AZOTH Total Focus is readily available at many online retailers. The nootropic can be purchased directly from AZOTH’s official website, but it may also be found in other online retailers, including Amazon, Walmart, eBay, and VitaminShoppe.


9) How Much Does Total Focus Cost?

One bottle of AZOTH Total Focus (15 capsules / 15 servings) is priced at $29.99.

You’re looking at around $60 a month for 30 servings. If you’re after a nootropic that contains more popular ingredients for the same price, we recommend checking out our BrainMD Brain and Memory Power Boost Review

How To Take

10) How to Take Total Focus

As a dietary supplement, take one (1) capsule 1 to 2 times daily, preferably with a light meal. Assess tolerance to one (1) capsule before taking two (2) capsules. Do not exceed two (2) capsules per day.

It is also worth mentioning that AZOTH recommends using Total Focus alongside other nootropics produced by the company.

  • Total Study Stack (Total Memory, Total Focus, and AZOTH 3.0) – A specially designed package for those in need to retain a lot of information before an important event (an exam or a presentation at work). It provides clean, long-lasting focus and boosts learning capacity and memory.
  • Silicon Valley Stack (Pure Energy, Total Memory, and AZOTH 3.0) – A stack created for those working in high-pressure environments looking to increase confidence, motivation, and mental stamina.
  • Presidential Stack (Total Memory, Total Focus, Pure Energy, and AZOTH 3.0) – Designed for elite-level professionals, athletes, workers, or gamers. It combines every single AZOTH product for long-lasting benefits in focus, recall speed, and energy.

11) What Users Are Saying

"I have more energy, and I'm definitely more focused and productive when I take this. I started with one pill at a time but started taking two at once, and it's made a big difference. The pills are easy to swallow and don't have much taste to me. You can definitely tell when they kick in." [Read full review]

---Dolly Stiles

"Provides a steady stream of mental energy that helps get complex things done quickly and efficiently. It doesn't give you an uncontrollable, jittery type of energy. It works very well for working on deadlines." [Read full review]

---John V.

"I feel very little effect. I have never felt that kick other reviewers talk about. I tried taking 2 one time and broke out in a cold sweat and felt dizzy. I've stacked it with nootropics, and I'm still taking it, hoping that one day it will magically kick in and do what the other reviewers say." [Read full review]


Bottom Line

12) The Bottom Line – “Does it Work?”

AZOTH Total Focus is one of those nootropic supplements that has gained much traction since its release. The formula is quite unique and incorporates a few potent ingredients with proven benefits for brain health, attention, focus, alertness, and concentration.

While more expensive than your average brain supplement (it will cost you up to $60 per month), AZOTH Total Focus may be a good choice for those looking for a good nootropic to support and improve their cognitive health.

5/5 - (1 vote)

Reference Sources

Notify of
Inline Feedbacks
View all comments