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Vitamin B-12 Sublingual Review – 8 Things You Should Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | What's Inside? | Claims | Contraindications | Price | Directions | Bottom Line

Nature MadeVitamin B-12 Sublingual is advertised as a dietary supplement, specifically designed to help restore proper Vitamin B-12 levels within the human body. This product is particularly suited for people over fifty years old or vegetarians who don’t receive proper intakes from their daily diets.Produced and sold by Pharmavite, this remedy can is available internationally under the brand name of Nature Made. As a business, Pharmavite was established as the first USA company to be USP approved, thus their products benefit from a higher quality and better manufacturing conditions than similar supplements of this type.

The core effects of Vitamin B-12 Sublingual, as claimed by the producers, are: maintenance of a healthy cognitive system, enhancement of cardiovascular health and improvement of the red cell blood formation processes. Vitamin B-12 is known to help maintain a healthy homocysteine level. High levels of homocysteine have been associated to cardiovascular distress (stroke and heart attacks) associated with several types of cancer, including pancreas, breast, and ovary.


1) What is Vitamin B-12 Sublingual?

Created to fulfill the needs of the people who suffer from a Vitamin B-12 deficiency, Vitamin B-12 Sublingual is found in the form of micro-lozenges. It addresses specifically to elders and vegetarians, due to the fact that they are more exposed to this deficiency from their diets or their incapacity of properly absorbing this vitamin.

The compound of this remedy works by regulating the homocysteine levels in the body, therefore improving cognitive functions and maintaining a healthy cardiovascular system. It is important to keep in mind that a Vitamin B-12 deficiency generally leads to some issues that can be sometimes irreparable, such as: weakness, depression, fatigue and chronic pains.In addition, this ingredient has been used as an energy booster because of the role it possesses within the energy metabolism. On the other hand, the nutrient doesn’t have any effect if there is no deficiency. Because of this, only people who have determined that they lack Vitamin B-12, may truly benefit from this treatment.

Recent research has discovered some potential positive effects of Vitamin B-12 Sublingual on treating cognitive diseases such as dementia, Alzheimer’s or mild depression. However, further studies are required.

What’s Inside?

2) What’s Inside Vitamin B-12 Sublingual?

Nature MadeVitamin B-12 Sublingual includes the following ingredients: Vitamin B-12 (1000 mg).

3) Is Vitamin B-12 Sublingual Right for You?

Designed to fulfill 16.66% of the daily Vitamin B-12 needs per micro-lozenge, Vitamin B-12 Sublingual is recommended specifically for vegetarians and people over fifty years of age. The main and only component of this formula is Vitamin B-12. Over the past decade, scientists have discovered the importance and necessity of this vitamin, as well as the consequences determined by its absence.

As studies have shown, Vitamin B-12 is necessary for the proper functioning of the nervous system by maintaining homocysteine levels and taking part in the red blood cell formation process. Also, scientists have discovered a connection between this vitamin and some cognitive dysfunctions, such as dementia and Alzheimer’s disease. Because a deficiency of Vitamin B-12 usually causes a homocysteine accumulation in the blood, the substances required to metabolize neurotransmitters decrease. This causes a decline in healthy cognitive functions.

Vitamin B-12 also possesses a role in energy metabolism and has been used for its booster properties, thus making this supplement reliable for people who suffer from weakness and fatigue. On the other hand, research has shown that if there is no nutritional deficit in the body, treatment based on Vitamin B-12 has no effect whatsoever.

Even though there are few contradictions suggested by the manufacturers in following this treatment, people should be aware that when combining dietary supplements with prescription drugs, there are some unwanted side-effects that may appear, such as reduced supplement Effectiveness and impaired supplement absorption. There are no online customer testimonials to support the efficacy of this natural remedy.


4) Vitamin B-12 Sublingual Claims

  • A visual guide is available to help customers correctly read the labels.
  • A coupon system is available for loyal clients.
  • The supplement is found in the form of micro-lozenges that are easily dissoluble.


5) Vitamin B-12 Sublingual Warnings and Precautions

  • There are no available reviews from people who have tried this product.
  • There is no money-back guarantee or return policy.


6) Vitamin B-12 Sublingual Price

Vitamin B-12 Sublingual can be found for purchase either on manufacturer website or other online or offline retailers. It is produced by bottles that contain fifty micro-lozenges, suitable for fifty days of treatment. Its price is moderate and can become even more affordable when the product is bought in larger amounts.


7) Directions For Taking Vitamin B-12 Sublingual

Side effects that may occur during this treatment are: diarrhea, stomach pains, nausea and itching.

Bottom Line

8) The Bottom Line – “Does it Work?”

Like many other dietary supplements found on the market, Nature MadeVitamin B-12 Sublingual addresses specific needs. It is suggested for people over 50 years old and vegetarians who don’t receive proper amounts of this vitamin from their daily diets.In addition, people who develop a deficiency of B-12 due to their body’s incapacity to absorb it, should consider following this treatment. On the other hand, the effects may lack if the person who takes this supplement already has elevate B-12 levels. There may be some side effects when utilizing Vitamin B-12 Sublingual, such as: diarrhea, itching or allergies and if any occur, it is advised to immediately stop.

4/5 - (2 votes)
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If you lack vitamin B from your diet.. this supplement is for you.

John W.

I’m 56 years old and I’ve heard about this product from a friend. At first I was skeptical, but I’ve decided to use it afterall. Now I can only say that I’m glad I did. It’s one of the best supplements I’ve ever tried. It improved my general state and now I feel younger than ever.