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Sublingual B12 Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Ingredients | Warnings | Cost | Directions | Verdict

Sublingual B12 is a supplement designed to help restore the energy level, improve concentration capacity and sharpen memory through a special sub-lingual delivery system (the tablets slowly dissolve under the tongue).

The manufacturing company, TriVita, is a Scottsdale, Arizona (U.S.) based company. It promotes and markets health and wellness products, such as vitamins for children and adults, nutrition or weight-loss products. The company functions on a multi-level-marketing business model. However, the official website fails to provide information on company history and potential medical research on the products.

Sublingual B12 use suggested is by placing one pill under the tongue and allowing it to dissolve. The manufacturer claims this is a patented formula that facilitates the absorption of B vitamins into the bloodstream, without an injection or swallowing a pill.


1) What is Sublingual B12?

Sublingual B12 is a complex of vitamins and acids combined into a unique formula which delivers B vitamins into the blood stream in a much more powerful way than swallowed tablets.

Whereas it is acknowledged that the B6 vitamin plays an big part in the biosynthesis of four important neurotransmitters (serotonin, epinephrine, norepinephrine and GABA), and that B-9 helps synthesize and repair DNA, produces healthy red blood cells, the manufacturer does not explain why and how the combination of the three vitamins actually works to sustain the product benefit claims.

Vitamin B12 is a water-soluble vitamin that helps the nerves and red blood cells stay healthy.
Deficiency of vitamin B-12 causes fatigue, weakness, nausea, constipation, irritability, loss of appetite, even more severe disorders such as dementia or incontinence.


2) Sublingual B12 Ingredients

TriVita Sublingual B-12 contains the following ingredients: Vitamin B6 (as pyridoxine HCL), Folate (as folic acid), Vitamin B12 (cyanocobalamin), Biotin, Mannitol, Sorbitol, Alphaketoglutarate, Stearic acid, Natural flavor, Malic acid, Magnesium stearate, Silica, Stevia leaf extract, and Sodium starch glycolate.

You can also find the more bioavailable form of B12 in mood-enhancing supplements like Mind Boost Day.

3) What Does Sublingual B12 Do?

Sublingual B12 is a combination of B-vitamins aimed to provide energy for the mind and the body.

While there is no denying that a person needs the vitamins offered in this supplement to feel energized and to be alert, consumers should try and get these vitamins from dietary intake. What a person gains from a supplement isn’t nearly as effective as what they get these vitamins from eating a variety of healthy foods. This product is not meant to replace a healthy diet.

It is also important to point out that TriVita was accused of being an MLM (multi-level marketing or pyramid company). Most of their sales are made by members and referrals of these members. This system affects the overall price per capsule. The company has to pay commissions to the sales people and to people they refer, which will be reflected in their products’ prices. For instance, the average price per capsule (in our case), taking into consideration the shipping and handling costs, is about $1/capsule. Many consumers can’t afford that.

There is little clinical evidence to support the manufacturer’s claims regarding this formula. While B-vitamins have proven to be effective, the whole formula needs additional research.

The recommended dose of this supplement is one tablet in the morning with food.

4) Sublingual B12 Benefits & Results

  • There is a 60 day refund period with a 100% refund on purchase price
  • Unique combination of ingredients
  • Distinctive delivery system

5) Sublingual B12 Product Warnings

  • No FDA evaluation or approval mentioned
  • Mixed reviews from consumers
  • Concerns expressed by consumers regarding some ingredients- Mannitol (multiple and severe side-effects identified)

6) Sublingual B12 Cost

Each bottle of Sublingual B12 contains 30 tablets, which should be enough for one month of treatment. Sublingual B12 is an expensive supplement.

You can buy TriVita Energy Now directly from the manufacturer or various online retailers. The manufacturer offers a members discount on each purchase. Some retailers may also offer free shipping for larger purchases.


7) Sublingual B12 Directions

The recommended dose of Sublingual B12 is two capsules daily, one in the morning and one at noon, placed under the tongue, not swallowed. Consumers have expressed mixed reviews regarding its effectiveness and occurrence of side-effects.


8) Our Verdict on Sublingual B12

Sublingual B12 is a dietary supplement designed to provide the nutritional support the body needs to increase energy levels and stamina, increase mental clarity and facilitate emotional balance.

The manufacturer makes several references to studies which support the claimed benefits of TriVita Sublingual B-12, stating there are conclusive results that this formula is easily absorbed into the bloodstream. However, medical research for this product specifically is not provided, but the manufacturer claims that the product features physician-approved formulas and a third-party testing and certification.

Also, the producer states that side effects are rare and are most-often related to an allergy associated with another ingredient in the dietary supplement. Consumer testimonials mention experiencing depression-related symptoms and physical weakness. As a precautionary measure it is recommended that a physician be consulted before starting using the product.

2.7/5 - (4 votes)
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Ernest Reid

B-12 should give you some type of boost right? I have been using the product and I am disappointed by my choice. Understand that this product gets placed under the tounge, and it takes up to 10 min to brake down. The company claims that this is as effective as a B-12 injection, but it falls short of the promise.


We’ve been using TriVita for years. I decided to try another product to cut down on costs. We suffered the consequences tremendously. TriVita is the very best product if you want energy and well being. In fact, the visual effects of using TriVita is immeidate. We look healthier and feel less stressed.

Martin Pope

I would not recommend taking these pills: didn’t work, they’re too expensive, the pills take a long time to dissolve under your tongue, etc…

wayne niemeyer

I have heard and read that folic acid causes prostate cancer. Yet it seems that many products have it as their folate ingredient. I am getting old enough to need folate with out it being its synthesized form called folic acid.
What do I do now? I’m really concerned about getting to much of this substance in my blood stream called folic acid.

Iulian (Editor)
Reply to  wayne niemeyer

Although people taking folic acid generally don’t notice any side effects, some may experience mild to moderate adverse effects while taking folic acid, including nausea, poor appetite, funny taste in your mouth, gas or bloating, trouble sleeping, and feeling depressed or overly excited. Taking extremely high levels of folic acid may increase your risk of developing cancer of the colon or rectum. However, most over-the-counter supplements of folic acid are 400 mcg tablets, which is far less than the maximum recommended daily dose. Generally, adults over 18, including pregnant women, should not take more than 1,000 mcg of folic acid a day.

Nina Viergever

is it alright for me to take b 12 when I am also taking Maxzide 25 mg.