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Sublingual Methylcobalamin B12 Review – 4 Things To Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Ingredients | Cost | Conclusion

Sublingual Methylcobalamin B12 is a high-potency dietary supplement developed by Applied Health to combat and prevent B12 deficiency and the problems caused by it. Methylcobalamin is the most concentrated form of B12 that can be assimilated by the human body and it has multiple health improving properties. Deficiency of B12 is very common today, as it can simply be caused by not keeping a very nutritional and balanced diet, but the lack of it can lead to several serious disorders, increasing cholesterol levels and the risks of heart attacks, strokes, and thrombosis.
The developer, the U.S. company Applied Health, specializes in the production of natural supplements that treat and prevent various disorders. Having over 20 years of experience in the field, the one thing that all their formulas have in common, besides the natural herbal ingredients, is the care and improvement of the immune system.
Sublingual Methylcobalamin B12 is a product that was designed to reduce cholesterol, stress, and anxiety levels by supplying your body with the intake of B12 needed. The effect of this dietary supplement is a long-term prevention from insomnia, loss of appetite, fatigue, constipation, or even depression. Of course, this supplement is not the solution for advanced levels of any of these symptoms, but only when they are caused by the deficiency of the B12 vitamin.


1) Sublingual Methylcobalamin B12 Ingredients

Sublingual Methylcobalamin B12 includes the following ingredients: Methylcobalamin, Mannitol, Xyletol, and Natural cherry flavor.

2) What Does Sublingual Methylcobalamin B12 Do?

Sublingual Methylcobalamin B12 contains Methylcobalamin, which is the formula with the biggest concentration of B12 vitamin. Being physiologically equivalent to B12, the main ingredient of this supplement is known to prevent or treat pathology arising from a lack of this vitamin but has also been used for many years in the treatment of diabetic and sclerotic disorders, and anemia.

The other ingredients, Manitol and Xyletol for example, are added to help put together the structure of the capsules and transport the medicine to the brain, reducing blood pressure and providing a proper assimilation of B12. This effective formula which Applied Health has created is designed in a sublingual tablet form to achieve a better and more direct absorption into the bloodstream by dissolving it in the mouth or under the tongue.

Besides its other properties already stated, Sublingual Methylcobalamin B12 regulates the immune system and provides the proper function of the brain and nervous system, also having a major role in red blood cell formation. Although there have not been known any side effects of the general consumption of Methylcobalamin, the manufacturer’s website does not offer any testimonials of previous consumers or studies and research on this product.

Even if the Institute of Medicine states that 10 to 12% of older people cannot absorb naturally occurring vitamin B12 in foods, medical advice is recommended before starting to take Sublingual Methylcobalamin B12 (both for young people and for people over 40).


3) Sublingual Methylcobalamin B12 Cost

Both in the U.S. and in more other countries where this product is exported, there are other supplements on the market with the same ingredients and smaller prices. A big advantage in the case of Applied Health’s supplement is that one single supply might be enough for more than a month since you are advised to use it only when symptoms appear, but anyway no more than twice per day.

Moreover, there are no shipping costs no matter where you wanted to be shipped. The manufacturer’s warranty, besides its reputation in the field of natural supplements, is the guarantee that, if you are not satisfied with the product, they will refund your money. In this way, the product quality is equivalent to its value in money.


4) Conclusion

Sublingual Methylcobalamin B12 promises to keep your cholesterol, anxiety, and stress levels under control and eliminate all the symptoms caused by the lack of B12 vitamin in your body. Considering its main ingredient, Methylcobalamin is the most concentrated easy to assimilate form of B12; this supplement seems to be the solution to many common symptoms that most of us experience. There were no side effects to this treatment so far. However, it is always the best choice to consult your doctor before beginning using it, just to make sure you are not allergic to one of the ingredients and that this is really what your body requires.

2.7/5 - (4 votes)
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My brother recommended this supplement when I began having cholesterol problems. It worked for him, but I haven’t experienced significant differences during the use.


I don’t know if Sublingual Methylcobalmin B12 really helped me because I have been taking other vitamins also, therefore I cannot guarantee for its effectiveness in my case.


My husband has had sleeping problems ever since he lost his job, but taking Sublingual Methylcobalmin B12, his sleep improved and he can now be more focused during the day.