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Solgar Phosphatidylserine Complex Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Formula | Claims | Cautions | Price | Directions | Verdict

Phosphatidylserine Complex Tablets is a formula marketed to provide the benefits of Phosphatidylserine, particularly to provide cognitive support. Solgar advertises the formula as a premium quality brain health product which contains a complex composed of Phosphatidylserine (100mg), Phosphatidylcholine, Phosphatidylethanolamine and Phosphatidylinositol.

Solgar is a nutritional supplements company founded in 1947. The company operates a modern manufacturing facility in New Jersey, and distributes its products throughout the world in over 60 different countries. Their product range includes targeted products such as kosher and vegetarian, as well as a wide range of vitamins, minerals and formulas which aim to treat specific health conditions.

No clear ailment claims are made by the manufacturer. Pregnant and nursing women or those taking any medication or having a medical condition are advised to consult a healthcare practitioner before taking any dietary supplement, including Phosphatidylserine Complex Tablets.


1) What is Phosphatidylserine Complex?

Phosphatidylserine Complex Tablets is a complex of phosphatides of herbal ingredients, vitamins and other nutrients designed to provide healthy memory function support during aging processes.

Phosphatidylserine has been the topic of numerous human clinical studies which tested the hypothesis that it may be able to assist with symptoms of dementia or reduce the risk of dementia and other cognitive dysfunctions (such as Alzheimer’s). Phosphatidylserine works by enabling brain cells to metabolize glucose and has been related to the synthesis of key neurotransmitters acetylcholine and dopamine, involved, in their turn in regulating key cognitive functions such as memory and attention and mood Although it is generally considered safe, it can cause insomnia and stomach upset.

Phosphatidylcholine is a major constituent of cell membranes and acts as a vehicle for essential fatty acids. Research has shown that Phosphatidylcholine is beneficial in depression, memory loss and neurological disorders, as well as in liver disorders (such as Hepatitis).


2) What Are Phosphatidylserine Complex Ingredients?

Phosphatidylserine Complex Tablets includes the following ingredients: Calcium (as dicalcium phosphate), Phosphatidylserine Complex, Phosphatidylserine, Phosphatidylcholine, Phosphatidylethanolamine, Phosphatidylinositol, Soy Lecithin enriched with Phosphatidylserine, Microcrystalline Cellulose, Dicalcium Phosphate, Vegetable Cellulose, Vegetable Stearic Acid, Silica, Vegetable Magnesium Stearate, and Vegetable Glycerin.

3) Does Phosphatidylserine Complex Work?

Phosphatidylserine Complex is intended to boost memory. Although it is believed that it helps in lessening the effects of Alzheimer’s disease, it does not help in advance states. The product might help maintain internal circadian rhythms and reduce the number of absence seizures when taken with GABA.

Early studies of phosphatidylserine distilled the chemical from the bovine brain; however, due to concerns of Bovine Spongiform Encephalopathy the products are now made from soybeans. In May 2003 the FDA stated that there is no significant scientific agreement among qualified experts that a relationship exists between phosphatidylserine and reduced risk of dementia or cognitive dysfunction.

However, Phosphatidylserine has been demonstrated to speed up recovery, prevent muscle soreness and improve well-being in athletes involved in cycling, weight training and endurance running. Phosphatidylserine supplementation promotes a desirable hormonal balance for athletes and might attenuate the physiological deterioration that accompanies overtraining and overstretching.

The first pilot studies indicated that Phosphatidylserine supplementation might be beneficial for children with attention-deficit hyperactivity disorder (ADHD). However, there is no sufficient evidence supporting these claims.


4) Phosphatidylserine Complex Claims

  • Free of corn, yeast, wheat, dairy products and gluten artificial preservatives, flavors or colors
  • Kosher certified and vegetable formula

5) What You Need to Know Before Taking Phosphatidylserine Complex

  • Pregnant, nursing, people under medication or ill should not take the supplement
  • Lack of public consumer reviews to assess its effectiveness
  • Potential side effects of the main ingredients

6) Phosphatidylserine Complex Price

Phosphatidylserine Complex 500 mg can be found for purchase directly on the manufacturer’s website or online from various other retailers. The product is currently being sold in bottles containing 30 tablets. The recommended dosage should not exceed 1-2 tablets per day.


7) Phosphatidylserine Complex Directions

The formula is free of corn, yeast, wheat, dairy products and gluten or artificial preservatives, flavors or colors. Consumer reviews are not available online. The manufacturer recommends taking 1 tablet daily. No side effects are associated to the formula.


8) Our Final Take On Phosphatidylserine Complex

Phosphatidylserine Complex Tablets is marketed as a premium quality brain health product. The manufacturer offers little information on product benefits, ailment claims or ingredients. There are no consumer reviews to evaluate the actual effectiveness of the formula, making it very hard to conclude whether the product works or not.

The formula contains a balanced blend of popular ingredients commonly associated to memory and mental function improvement such as Vinpocetine, DMAE, Phosphatidylserine or Vitamin B6 and B 12. The formula is therefore probably going to produce some effects in the benefit areas described by the manufacturer. However, to what extent the product will accomplish its purpose cannot be established, particularly since there are no consumer reviews to validate its effectiveness.

Given that the product contains soy and caffeine and that it may interact with certain types of medication, we recommend caution.

While phosphatidyl is great as a nootropic, it’s not exactly what you want if you prefer to have a relaxing effect. For that, you need a nootropic like NeuroScienceTravaCor powered by GABA.

5/5 - (1 vote)
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Comes in pretty handy, daily excercise has never been as easy before.