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Sheer Strength Nitric Oxide Review – 8 Things You Didn’t Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Ingredients | Pros & Cons | Contraindications | Cost | Dosing | Bottom Line

Nitric Oxide (NO2) is designed to help boost muscle growth, improve recovery times after intense physical workout, while also increasing workout performance and energy. The main ingredient is L-Arginine which is converted to Nitric Oxide once inside the body. The numerous benefits of NO2 derive from its vaso-dilatating properties, and may also include superior sexual performance, and better cardiovascular function. We will discuss these benefits in the following sections of the review.

The formula has been declared No1- best Nitric Oxide supplements by Amazon.com, and indeed enjoys a lot of popularity, with more than 2,500 testimonials and more than 100 questions asked and answered by consumers or manufacturer representatives.

The formula is designed to help adult athletes, bodybuilders, fitness and physical activity enthusiasts reach their workout goals and boost performance of their training sessions.

Sheer Strength Lab is a sports nutrition company dedicated to offer customers muscle building supplements that are based on scientific research. The company is so confident in their formulations that they offer a 30-day 100% money back guarantee for used and unused bottles (even if the bottle is returned empty).


1) What is Nitric Oxide?

Nitric Oxide is produced during the metabolism of L-Arginine, and therefore quantities available highly depend on each individual’s metabolic function. L-Arginine is an amino-acid that is converted in the body into Nitric oxide, which causes the blood vessels to widen and hence improves blood flow. The amino-acid stimulates the release of insulin, the growth hormone, and other substances in the body.

Nitric oxide, dietary supplements are generally marketed as physical performance enhancers. They are claimed to help increase the intensity of the workout session, while also promoting better oxygen delivery to the muscles, and enhancing the muscle building capacity.

As Nitric Oxide (NO2) these supplements usually feature L-arginine or L-arginine alpha-ketoglutarate. NO2 stimulates vaso-dilation, meaning it increases the diameter of blood vessels which pump up more blood to the muscles during exercise, as needed. Scientific evidence of these effects of NO2 are scarce and often conflicting, although consumer testimonials from athletes and sports enthusiasts generally praise its usefulness. Nitric Oxide (NO2) has received more than 2,500 such testimonials, and the general score is 4.4 out of 5 stars


2) Nitric Oxide Ingredients

Nitric Oxide (NO2) contains the following ingredients: L-Arginine HCL, L-Arginine AKG, L-Citruline Malate, pine Bark extract, Gelatin (capsule), rice flour, magnesium stearate, and silicon dioxide.

3) Does Nitric Oxide Work and it is Safe?

NO2 is a product that results from L-Arginine metabolism. The amount each capsule of Nitric Oxide (NO2) contains hence actually depends on how efficiently each individual metabolizes L-Arginine. To be more specific, there is a direct relationship between the efficiency of the metabolic function and the level of NO2 conversion. One will not metabolize NO2 for instance if the physical activity level is inadequate to create the demand for NO2.

Nitric Oxide, also known as Nitrogen Oxide works by facilitating artery relaxation and better functioning, hence improving blood flow throughout the entire body, including muscles. This is why Nitric oxide is a popular muscle building supplement that helps you grow stronger faster, and put more energy in the workout session. It’s vasodilatation properties make it highly recommendable for cardiovascular health, while there are accounts of it increasing blood flow to the male sexual organ for enhanced potency.

The manufacturer claims you will feel the core benefits within the first week of use and numerous testimonials even claim that it took one or two days to see tangible results.

There is a 30-day money back guarantee available for this supplement, which covers used and unused bottles as well. The manufacturer specifies on the label to talk to a licensed health care professional if you have suffer from health conditions including but not limited to diabetes, seizure disorder like epilepsy, prostate enlargement, heart arrhythmia, heart disease, or liver problems. They also recommend that pregnant or lactating women or those under the age of 18 not use the formula. Side effects reported are rare and minor and may include stomach upset and headache.

Pros & Cons

4) Nitric Oxide: Pros and Cons


  • A 30-day money back guarantee is available, including if you return empty bottles
  • More than 2,500 consumer testimonials and more than 100 questions asked on Amazon
  • The title of “Best Seller” offered by Amazon


5) Nitric Oxide Warnings and Precautions

  • The moderately high price for one month of use
  • The formula should be used with caution by patients suffering from a previous health condition

6) Nitric Oxide Cost

You can get the 120 capsules bottle for roughly $50. The daily dose is 4 capsules per day, taken either right before workout sessions or in the morning, on non-workout days. One bottle should last 30 days in these conditions, making the daily cost rise to $1.6, which is moderately high. The formula can be directly purchased from the manufacturer’s website or prom other online retailers. Discounts and promotional offers may also be available – for instance at the time of this review you can get the supplement for 58% of its normal retail value which is a consistent price reduction.


7) Nitric Oxide Serving Size

Short term use of amino-acid supplementation is relatively risk-free, however in case you suffer from certain conditions like blood pressure or erectile dysfunction you may want to avoid use. Pregnant and nursing women as well as people under the age of 18 should not use the supplement either.

Bottom Line

8) The Bottom Line – “Does it Work?”

Although not without risks or associated side effects Nitric Oxide supplements are credited for increased vascularity, faster recovery times post-workout and better post-workout “pump” which seem to convince a lot of physical exercise enthusiasts to use them. Scientific research is limited nonetheless and it is best to seek a physician’s guidance before starting use.

Sheer NO2 by Strength Labs is a muscle enhancing supplement that enjoys great popularity among sport enthusiasts if we are to look at the large number of consumer testimonials (mostly positive), as well as to the company’s own confidence in its product (the generous money back guarantee policy).

3/5 - (1 vote)
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