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Puritan’s Pride Neuro-PS Review

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Ingredients | Benefits | Contraindications | Price | Directions | Conclusion

Neuro-PS represents a product offered to the everyday customer to improve memory, sharpen mental focus, help with learning abilities, and promote mental clarity. The business behind this remedy is called Puritan’s Pride, the same company behind Super Snooze.

Founded approximately 40 years ago with the stated mission of offering the finest quality nutritional supplements available on the market at the best value, Puritan’s Pride, unfortunately, fails to provide its ingredients, clinical studies, and formulation specifics, or other information that may support its claims.

The official website clearly stated that there is little evidence from the FDA when it comes to the fact that this supplement can help reduce risks of cognitive dysfunctions in the elderly.

Furthermore, the producer doesn’t list any potential side effects that may appear when following this treatment. Still, it advises pregnant or lactating women to consult their personal healthcare before using this supplement. If adverse reactions occur, it is better to discontinue the treatment and consult a medical doctor.

Neuro-PS is based on the beneficial effects of Phosphatidylserine, a natural substance located in brain cell membranes. Because phosphatidylserine levels decline with age, people usually try to take nutritional supplements to balance them.


1) Neuro-PS at a Glance

The main ingredient of Neuro-PS is Phosphatidylserine, which is a phospholipid that offers physiological, structural, and biochemical support to the cell membranes, specifically the ones in the brain.

Although the manufacturer’s claims are that this formula should enhance memory, sharpen mental focus, support learning abilities, and promote mental clarity, there are few studies done on the ingredient and not on this product that may provide positive results.

For example, Phosphatidylserine is currently used in treating the age-related decline in mental functioning, Alzheimer’s disease, attention-hyperactivity disorder, enhancing athletic performances, and improving thinking skills in young people.

Because it is a chemical with numerous functions in the body, Phosphatidylserine represents a part of the cellular structure, thus being a key for its maintenance, specifically the brain. Even though this chemical can be made by the body, it gets most of what it needs from foods.

Although this ingredient was initially manufactured from cow brains, it is currently obtained from soy or cabbage because there was a significant concern that the initial sources might have triggered mad cow disease infections.


2) Neuro-PS Ingredients

Neuro-PS contains the following ingredients: Neuro-PS (Phospholipid Complex from Soy Lecithin) (Standardized to contain Phosphatidylserine, 300 milligrams), Soybean Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Vegetable Cellulose, Dicalcium Phosphate, Calcium Carbonate, Natural Caramel Color, Vegetable Magnesium Stearate, Titanium Dioxide Color, Silica, and Calcium Silicate.


3) Neuro-PS Benefits & Results

  • It focuses on providing Phosphatidylserine to balance its levels
  • It comes in the form of softgels which are easy to swallow
  • The price of the supplement is affordable when purchased in large amounts because of the additional discounts and promotions

4) Neuro-PS Warnings and Precautions

  • The manufacturer claims weren’t entirely FDA-approved
  • There aren’t any mentioned side effects
  • Pregnant and lactating women should avoid this treatment

5) Neuro-PS Price

Neuro-PS is an average-priced supplement. The formula is available in bottles of 30 and 60 capsules, featuring 100 mg active substance PS.

Neuro-PS can be purchased directly from the manufacturer’s website or from various other online retailers. Some retailers may offer additional discounts and promotions able to reduce the overall cost per serving further.

For instance, one retailer currently advertises a “buy one get two free” promotional offer. In contrast, another offers 60% off the standard price for those who order at least six bottles of the product.

An additional discount of 10% applies in the case of referral. The discount applies to both the person referred and to the one referring him/her. In case a customer is not satisfied with the supplement, it can be returned (partially used included) within a one-year time frame. A full refund is granted, less shipping and handling costs.


6) Directions For Taking Neuro-PS

Even though it is possibly safe for most people, Neuro-PS can occasionally cause side effects such as stomach upset or insomnia, specifically in doses over 300 mg.


7) Conclusion

All in all, Neuro-PS represents a product whose beneficial effects are based on a critical ingredient called Phosphatidylserine, which actually gives the supplement part of its name.

It was basically designed to enhance cognitive functions such as mind sharpening, memory, concentration, thinking, and learning abilities.

It’s a producer based the design on the fact that people lack proper levels of Phosphatidylserine with age. Because of this, they require some form of nutritional supplementation.

Even though its manufacturer’s claims put the product in an excellent light, further research is required to generally determine the efficacy of Puritan’s Pride Neuro.

4.3/5 - (3 votes)
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Geraldine King

I’ve been taking Neuro PS Gold for a week and I have had a headache ever since. Well, I stop taking it for a couple of days just to see if it was the vitamin and sure enough I didn’t have the mental fog.

Title for your comment
Side effect of Neuro PS Gold
Have you tried this product?

Phosphatidylserine is a great supplement and in this blend, my mind was clearer and focused. Thanks!

Sam Thompson

I felt the difference and saw the results within days. This had the ingredients (PS+) that are proven to work at a good price offer.
This is the best supplement I have tried for brain function


My sleeping/going to sleep is really bad – might it have something to do with NEURO PS?

Iulian (Editor)
Reply to  lotte

Phosphatidylserine is the primary ingredient in Neuro-PS. Phosphatidylserine can cause side effects including insomnia and stomach upset, particularly at doses over 300 mg. Hope this helps!

Michael Crist

I’m a regular buyer of Puritan’s Pride products. In general I’m very satisfied with the quality of their products. However, the onus for determining which supplements to buy and their effectiveness rests solely with consumers.

Neuro-PS Gold is a relatively expensive supplement compared to other essentials like Vitamin D & Magnesium.

I bought the product when it was on sale, and quite frankly I’ve found no justification for a re-order.

Further, I’ve had a prolonged bought of diarrhea for the past two months, and suspect one or more of my supplements as the culprit.

[This deduction followed a visit to my gastroenterologist, and multiple blood & stool tests, which all came back negative for such things as Celiac Disease.]

Many consumers complain about the “oiliness” of the capsules, and combined with Triple Omega & Medium Chain Triglycerides [MCTs]… I’m probably getting too much in the way of “oils”.

So, without any definitive results which justify the expenditure… I would recommend trying another less expensive alternative.


I’m only taking one-third of the recommend daily dosage [i.e. one capsule per day vs. three]. Yet that’s still 500mg, and most recommended daily dosages I’ve seen on the internet say 300 mg. is enough.


I found Neurons PS to be a decent supplement. I did increase focus and awareness. However I think it is wise to down dose off the supplement for a few months and then get back on it. It appears to be ineffective after long term usage, and it hampered my multi-tasking abilities because I had the urge to only focus in on one thing at a time. I also advise not to take too much, you tend to be more focused on one thing and pay less attention to what’s around you. That could be good and bad.
Overall I give it a B if used properly.

Harry Houdini

I tried Neuro-PS, and it didn’t work. It would have depressed me, but I forgot about it. Having a bad memory ain’t so bad after all.


I’ve been taking this product for a week and recognize a slight improvement in mental clarity. As with all medications, supplements, vitamins and foods results or reactions will vary from one indivdual to another based on deficiencies or body chemistry. It is my belief that mental decline is a natural age related process and vitamin therapy may reverse or slow down this process if QUALITY ingredients are used (which are usually costly) in the formula. As in most cases you get what you pay for.
To early to recommend this product but I will post postive or negative results after a few months.