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PhosSerine DHA Supreme Review – 7 Facts to Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Formula | Health Benefits | Cautions | Price | How To Use | Bottom Line

PhosSerine DHA Supreme is designed to support memory, focus and concentration and is advertised as the first Phosphatidylserine (PS) supplement that is molecularly bound with long chain omega 3 fats, specifically DHA.

The manufacturer, Crayhon Research, argues that the formulas based on PS available on the market were using a soy extract, without the covalently bound DHA. However research that showed incredible results of PS used bovine extracted Phosphatidylserine bound with DHA (meanwhile bovine extraction gained less and less popularity due to concern of infections such as mad cow disease).

Crayhon Research claims to be a worldwide leader in advanced brain nutrition and supplements. The company was founded in 2003 in Nevada, USA and currently manufactures a wide range of anti aging vitamins such as Brain Vibrance, Brain Vibrance Supreme, MCT Oil and Carnitine + Biotin.


1) PhosSerine DHA Supreme at a Glance

PhosSerine DHA Supreme is a combination of Phosphatidylserine and the Omega-3 fatty acid DHA. This product does not contain wheat, dairy, corn, artificial colors or flavors.

DHA is an essential Omega-3 fatty acid which is a major structural fat of the brain and the retina, accounting for up to 97% of the Omega-3 fats found in the brain and up to 93% of the Omega-3 fats found in the retina. Its importance is hence crucial to normal brain and eye function.

Phosphatidylserine is a naturally occurring phospholipid. It can be synthesized in the body from the fatty acids stored in the adipose tissue or in fat cells. Although research is still needed to establish a direct relation between the two, Phosphatidylserine is believed to have a protective effect on the brain and central nervous system by promoting proper health and maintenance of myelin sheaths (the protective covering around nerve fibers). Also, there are voices that support the theory according to which it increases levels of Acetylcholine, a neurotransmitter involved in learning and memory. It has even been argued that PD assists against symptoms of Alzheimer’s disease and age-related mental decline, but insufficient evidence exists.


2) What Are PhosSerine DHA Supreme Ingredients?

PhosSerine DHA Supreme includes the following ingredients: PhosphatidylSerine (soy) 100 mg, DHA (Docosahexaenoic Acid) 20 mg, Dicalcium phosphate, cellulose, maltodextrin, Silicon Dioxid and, Magnesium Stearate.

If you want to see a more focused formula including both DHA and phosphatidylserine, check out our Sharp Thought review or Blue Star Elevate review.

Health Benefits

3) PhosSerine DHA Supreme Health Benefits

  • Unique combination of PS and DHA for increased effectiveness
  • Researched ingredients
  • No wheat, dairy, corn, artificial colors or flavors

4) What You Need to Know Before Taking PhosSerine DHA Supreme

  • Expensive formula (60 capsules cost approximately $50 which at maximum 5 capsules a day dosage is sufficient for 12 days of treatment)
  • Lack of consumer reviews to assess PhosSerine DHA Supreme’s effectiveness

5) PhosSerine DHA Supreme Price

PhosSerine DHA Supreme is an affordable supplement sold in different size bottles, either containing 30 vegetarian capsules or 60 vegetarian capsules. The product is available for purchase on the manufacturer’s website or from various online distributors.

How To Use

6) How to Use PhosSerine DHA Supreme

No PhosSerine DHA Supreme reviews are available for consultation. The manufacturer recommends taking one to five capsules per day.

Bottom Line

7) The Bottom Line – “Does it Work?”

PhosSerine-DHA Supreme is advertised as the first fully conjugated PhosphatidylSerine-DHA supplement. According to the manufacturer, the formula provides potent PS and is uniquely designed to nourish and support brain wellness, memory and concentration. Unfortunatelly, there are no consumer testimonials to support these benefit claims. No other empirical evidence is brought by the manufacturer to support the claims.

PhosSerine DHA Supreme is an excellent choice for those with allergies (having a low allergy potential). It is likely to work for some people, however there is no guarantee since every patient is different. This is why we strongly recommend caution, and advise you to see a specialist prior to use.

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