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Nature Made L-Lysine Review – 8 Reasons Why

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | Ingredients | Pros & Cons | Contraindications | Cost | Directions | Bottom Line

L-Lysine is a supplement manufactured by Nature Made and is designed to provide support for the organism to manufacture proteins. Being an essential amino acid, L-Lysine can also promote a state of well-being, improving mood and several bodily functions. This product can be beneficial for virtually everyone, provided the instructions given by the manufacturer or a medical professional are followed.

Nature Made is a brand of Pharmavite, a company with over 30 years’ experience in developing and manufacturing health supplements. The company has a very good reputation of providing quality items at moderate prices. It has received many awards for its products, and they follow strict rules regarding their manufacturing process, selecting only the best quality ingredients.


1) L-Lysine Quick Facts

L-Lysine has an amino acid ingredient formulation containing Lysine, one of the nine amino acids essential to the body.

According to medical studies, Lysine is a potent anxiolytic, reducing stress and improving the general mood of people. Deficiency of Lysine has been shown to increase anxiety levels, as studies performed both on humans and animals have proven. Frequent consumption of Lysine might also reduce the frequency of sores for those affected with herpes simplex infections.

The human body cannot produce Lysine on its own, therefore a daily intake of the amino acid is necessary through foods and supplements. While there are many food sources of Lysine available, people relying mostly on a grain-based diet can experience a deficiency of the substance, requiring additional nutritional sources.


2) L-Lysine Ingredients

L-Lysine contains: Lysine Monohydrochloride, Cellulose Gel, Stearic Acid, Crospovidone, Croscarmellose Sodium, Silicon Dioxide, Hydroxypropyl Methylcellulose, Magnesium Stearate, and Polyethylene Glycol.

3) Does L-Lysine Work?

L-Lysine contains Lysine Monohydrochloride as the only active ingredient in the formula. Each tablet was designed to provide the dieter with 1000mg of this essential amino acid.

L-Lysine is an essential amino acid. Our bodies can not produce it, therefore, it must be obtained from the diet. L-Lysine is one of the many amino acids that the body needs for constant tissue repair and growth and is also involved in the production of antibodies, certain hormones, and enzymes. So far, scientists have identified this amino acid to be helpful in the reduction of the severity of herpes-related cold sores, in the synthesis of collagen, in the treatment of certain infections, and in the maintenance of healthy skin, ligaments, and tendons. There is also evidence that suggests this essential amino acid may be used to promote good bone health.

Please note that it ‘s hard to choose L-Lysine supplements. Most importantly, the pills of L-Lysine should be enteric coated so that they are not destroyed by the gastric acid. Unfortunately, the manufacturer does not provide that information about their product. The suggested dosage for L-Lysine is one tablet daily, with a meal.

There are testimonials posted online about L-Lysine. What is being stated includes:

  • The product is fine, both my wife and I take it

  • I am happy with my results

  • Very good for herpes-related cold sores

  • Best treatment I’ve found yet

Pros & Cons

4) L-Lysine: Pros and Cons

  • Available in 500 mg and 1000 mg doses
  • Attractive price: a bottle costs $6.29 and can last up to three months
  • Contains no artificial colors, flavors or preservatives no yeast and no gluten
  • Reputable manufacturer, having over 30 years’ experience in producing supplements
  • Money-back guarantee, if you are not satisfied with the product you can return it to the manufacturer


5) L-Lysine Warnings and Precautions

  • Purchasing directly from the manufacturer is not possible
  • Shipping costs vary among different suppliers
  • Provides maximum benefit to people suffering from a Lysine deficiency


6) How Much Does L-Lysine Cost?

L-Lysine is an average-priced supplement. Each bottle should last you approximately two months at the recommended dosage considering that each one contains 60 tablets.

Unfortunately, the manufacturer does not sell this product directly. However, it is commonly found in stores, and it may also be ordered from numerous online retailers. Please note that the price usually varies between retailers. You may be offered a 30-days money back guarantee from individual retailers.


7) L-Lysine Directions

So far, research has not revealed any negative interactions for Lysine-based products, the supplement being considered safe for all age groups. The recommended dose for L-Lysine is one tablet daily, taken with a meal.

Bottom Line

8) Our Bottom Line

L-Lysine is one of many products that can provide great benefits for people suffering from a deficiency, but might not be as effective in the case of a person that has a balanced diet that provides them with all the needed amount of nutrients. That being said, there are still many people that have taken L-Lysine and had positive effects, such as reducing the frequency and duration of herpes-related cold sores, improving moods and providing customers with a general sense of well-being.

For any information you require regarding the product you can contact Nature Made or consult your doctor.

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