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MigreLief Review – 9 Things You Didn’t Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | What's Inside? | Side Effects | Cost | How To Use | Verdict

MigreLief is advertised as the first comprehensive herbal supplement to support cerebrovascular tone and healthy brain-blood vessel function. Akeso Health Sciences make MigreLief.

The formula is recommended for those who suffer from chronic migraines and claims to decrease the number and intensity of migraines in three to six weeks, but is this true? Does MigreLief work? Read on to find out.


1) What is MigreLief?

MigreLief is a nutritional dietary supplement designed to treat migraines while supporting cerebrovascular tone. The formula contains three core ingredients; Riboflavin, a B vitamin, Magnesium, a mineral, and Puracol, a plant extract, all of which work to relieve migraines, prevent spasms of blood vessels and keep them open and toned.

What’s Inside?

2) What’s Inside MigreLief?

MigreLief includes the following ingredients: 400mg Riboflavin, 360mg Magnesium citrate, and Magnesium oxide, and 100mg Puracol Feverfew.

3) What Does MigreLief Do?

MigreLief contains three active ingredients; Puracol, Magnesium, and Riboflavin, which work in different ways to help relieve symptoms of migraines.

  • Puracol is a patented formulation of the Feverfew plant. Feverfew has been traditionally utilized to remedy inflammation, menstrual cramps, and fever and relieve migraines.

The particles in Feverfew keep the blood vessels properly toned while reducing the length, frequency, and severity of migraines by inhibiting the synthesis of prostaglandins and the release of histamines and serotonin, which play critical roles in the pain pathway and can cause vasospasms.

  • Riboflavin, or Vitamin B2, is involved in cellular energy generation. Persons with poor cerebrovascular tone and migraines have also been noted to suffer from a deficiency of mitochondrial energy reserves, which Riboflavin works to resolve.

  • Magnesium helps blood vessels relax and relieves vasospasms that can lead to migraines.

Side Effects

4) Side Effects of Using MigreLief

Two of the core ingredients in MigreLief, Magnesium and feverfew, may cause side effects like nausea, stomachaches, and diarrhea.

Where to Buy?

5) Where to Buy MigreLief?

You can buy MigreLief from the Akeso Health Sciences website or Amazon.


6) How Much Does MigreLief Cost?

MigreLief costs $24.95 for a 60-count bottle.

How To Use

7) How to Use MigreLief

Take one caplet of MigreLief in the morning and one in the afternoon or evening with food, allowing six to seven hours between doses.

8) Variations of MigreLief

MigreLief comes in four different formulations.

  • MigreLief Original

  • MigreLief+M

  • Children’s MigreLief

  • MigreLief-NOW


9) Our Verdict on MigreLief

MigreLief is a patented formula designed to assist with managing chronic migraines and preventing new-onset migraines. It contains a combination of a vitamin, plant extract, and mineral to provide a threefold relief from migraines.

MigreLief is likely to work as its core three ingredients, Pruacol Feverfew, Magnesium, and Riboflavin, have been researched and proven effective in migraine prevention and treatment. Also, most consumer testimonials agree that the formula is effective and as beneficial as it claims.

3.1/5 - (17 votes)
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I feel some changes, but nothing worth mentioning yet. Still waiting for the four to six weeks effect guarantee.

Rachel A

I am glad that Migrelief is a supplement that has positive effects on me, after just three weeks of use I feel less stress and more focus. It’s great.

Reply to  Rachel A

I am feeling relief already i have had migraines my whole life and have many triggers it is so debilitating. So far so good. Fingers crossed.

Maggie O'Neil

Manufacturer of the MigreLief patented formula (Magnesium, Riboflavin and Puracol Feverfew) is Akeso Health Sciences, LLC. Akeso also manufactures Children’s MigreLief, MigreLief+M (menstrual migraines) and MigreLief-NOW (fast-acting acute/rescue formula)

Pamela Gail

You have mistated Quantum Health as the manufacturer of MigreLief when in fact, Akeso Health Sciences, LLC is the only patent-holder and manufacturer of MiHow greLief with Puracol™. P.S. Great product for migraines!