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Doctor’s Best NAC Detox Regulators Review

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | What's Inside? | Benefits | Cautions | Price | Directions | Verdict

Best NAC Detox Regulators is a supplement which promises to boost glutathione production while promoting the healthy functioning of important proteins. It’s manufactured for California company Doctor’s Best, who is located in Orange County. They claim to combine traditional wisdom with up to date research. This ensures potentially quality strategies for achieving optimal health. People who would want this supplement are looking for a quality way to get an important antioxidant into their diet.


1) Doctor’s Best NAC Detox Regulators Quick Facts

N-Acetyl-L-cysteine (NAC, acetylcysteine) is a derivative of cysteine found in dietary supplements like this one. It can be used as an antidote for acetaminophen overdose, to loosen thick mucus, and may help with certain obsessive-compulsive disorders. Its main use here is to help your body create cysteine.

Cysteine (Cys) is a semi-essential proteinogenic amino acid. It’s found in many high protein foods and can by synthesized within the human body. Glutathione (GSH) can be created from cysteine, glycine, and glutamic acid. All three are readily available from common foods, although cysteine is the most difficult of the 3 to find. Glutathione is an antioxidant found in many living organisms; it can also help with various biochemical reactions. Antioxidants, in safe amounts, can reduce damage to your cells. Some people believe antioxidants can help prevent or cure cancer, although this is unlikely, and the research is inconclusive. Doctor’s Best says that cysteine (as l-cysteine) is too unstable to be used in dietary supplements by itself, so it’s better to ingest ingredients that convert into it. Glutathione is possibly best when your body makes it. Cysteine can also be used in processes that create alanine and sulfide. Do note that N-Acetyl-L-cysteine can cause side effects like nausea, rash, fever, and vomiting.

What’s Inside?

2) What’s Inside Doctor’s Best NAC Detox Regulators?

Best NAC Detox Regulators contains the following ingredients: Selenium, Molybdenum, N-Acetylcysteine, Modified cellulose (vegetarian capsule), citric acid, natural vanilla flavor.

3) Does Doctor’s Best NAC Detox Regulators Work?

The vegetable capsules include selenium (SelenoExcell), molybdenum (molybdenum glycinate), and N-Acetylcysteine (NAC). NAC promotes the production and utilization of glutathione, an important antioxidant. Doctor’s Best says “Glutathione is the most highly concentrated antitoxin and antioxidant within human cells, and adequate glutathione is a must for good health.” But one might wonder about the other two active ingredients.

Molybdenum is a metallic element usually found in steel alloys. However, it’s considered an essential trace element for life. It’s necessary for humans and is found in many of our foods, such as eggs and sunflower seeds. Deficiencies are almost unheard of, and the average daily intake is usually between 76 and 240 mcg. The recommended dietary allowance for most adults is 45 mcg a day, which means Best NAC Detox Regulators contains too much. They list 50 mcg as 67 percent of your daily value, which is false. (50 mcg is 111 percent of your daily value unless you’re pregnant or breastfeeding.) Doctor’s Best could significantly reduce the amount of molybdenum, since most people already get more than daily recommended amount. Selenium is in the same spot, since it also contains 50 mcg, On average, people in the USA get 125 mcg a day from food and water, which is more than twice the recommended daily amount. And again, Doctor’s Best incorrectly states the daily value. 50 mcg selenium is 91 percent of your daily value, not 71. Very few people need supplements for molybdenum or selenium.


4) Doctor’s Best NAC Detox Regulators Benefits & Results


  • Very low priced vegetarian capsules with vanilla flavor.
  • Good supplement for people with Crohn’s disease, because of the selenium and molybdenum.


5) What You Need to Know Before Taking Doctor’s Best NAC Detox Regulators

  • Best for people over the age of 40. They’re the most likely group to suffer from deficiencies of glutathione and cysteine.
  • Too many antioxidants in your body can aid the growth of malignant tumors. You have to be careful about how many vitamins and antioxidants you ingest. Taking too much can be bad for you. Likewise, this supplement has high levels of selenium and molybdenum. Taking more than 1 or 2 capsules a day could be unsafe for many people.

6) Doctor’s Best NAC Detox Regulators Price

These are extremely inexpensive and affordable on any budget. Most people will take only one capsule a day, making this a two month supply. Even if you take 2 to 3 capsules daily, the price is still very low. Do note that you should not take more than 1 capsule a day unless your doctor recommends otherwise. It’s very difficult for many people to get to the point where they need supplements with selenium and molybdenum, so taking too much could lead to complications. Always consult your doctor if you have any doubts about something.


7) Directions For Taking Doctor’s Best NAC Detox Regulators

In short: NAC is here to make the amino acid cysteine, which makes the antioxidant glutathione, which can benefit people in various ways.


8) Our Verdict on Doctor’s Best NAC Detox Regulators

This is a product for long term health, like omega-3 supplements. You may not notice results right away, unless you’re using this to help with sinus problems. The only obvious problem is that despite how long Doctor’s Best has been in business, they’ve mislabeled the daily values. For most adults, if you take this, you’ll get 111 percent of your molybdenum and 91 percent of your selenium. However, Best NAC Detox Regulators can help in a lot of ways, and it’s one of the least expensive supplements you can find.

2.6/5 - (10 votes)
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