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CogniBoost Review – 12 Facts to Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Overview | What's Inside? | Health Benefits | Safetiness | Cautions | Cost | Shop For CogniBoost | Suggested Use | Conclusion

The idea that a supplement can supersize human intelligence is decidedly science fiction. However, many real-world researchers and supplement-makers are currently working to develop medicines, supplements, and other substances designed to improve various aspects of cognition.

CogniBoost is advertised as one such nootropic designed to improve attention, alertness, memory, and support cognitive function using only natural ingredients.


1) Quick Overview

The word “nootropic” comes from the Greek word “noos” meaning “mind” and “tropein,” meaning “towards,” and was invented in 1972 by the Romanian scientist Corneliu Giurgea to define a class of composites that selectively act “towards the mind.”[1]

Today, there are dozens of over-the-counter (O.T.C.) products – many of which are marketed widely in stores or online – that claim to boost decision-making, memory, creativity, or other high-level brain functions.

CogniBoost is a nootropic developed by Dr. Sinatra, who claims to be “America’s #1 integrative cardiologist.” Dr. Sinatra sells a lineup of all different multivitamins, herbal supplements, Omega-3’s, and treatments.

The formula developed by Dr. Sinatra includes several well-known ingredients in brain supplements like Acetyl L-Carnitine, which was added to improve reaction times, memory, and focus.

2) How Did CogniBoost Start?

Stephen T. Sinatra, M.D., F.A.C.N., F.A.C.C., C.B.T., C.N.S., is a board-certified cardiologist, certified nutrition and anti-aging specialist, and certified bioenergetic psychotherapist. He has authored several publications and medical periodicals and has lectured and facilitated workshops worldwide.

Dr. Sinatra has been a featured guest on many television and national radio shows, including M.S.N.B.C., CNN, the Dr. Oz, Fox on Health, 700 Club, The Doctors, and The Today Show.

Dr. Sinatra is the founder of HeartMD Institute. According to the official website, HeartMD Institute’s mission is to educate patients, and medical professionals alike about integrative medicine, with distinct focuses on metabolic cardiology and energy medicine.

Additionally, HeartMD Institute strives to inspire a restructuring of the doctor/patient relationship where they actively engage in the patient’s healing process.[2]

What’s Inside?

3) What’s Inside CogniBoost?

CogniBoost includes the following active ingredients:

  • Acetyl L-Carnitine 500 mg
  • Blueberry fruit extract 300 mg
  • Cereboost American Ginseng extract 200 mg
  • Meriva Pythosome (Turmeric extract and Phosphatidylserine) 100 mg

Other inactive ingredients include microcrystalline cellulose, silicon dioxide, gelatin, and magnesium stearate.

If you prefer a more complex formula, we recommend checking our Dynamic Brain review.

4) Does CogniBoost Work?

Acetyl L-Carnitine (the most bioavailable form of carnitine)[3] is the primary ingredient in CogniBoost.

Carnitine is an amino acid-like compound that plays a critical role throughout the body. It’s obtained naturally from certain foods (mostly red meat). But some people (especially those with a diet that doesn’t include meat) don’t get adequate amounts of carnitine to support optimum brain functions.[4][5]

By adding Acetyl L-Carnitine-rich foods to your diet or supplementing with this amino acid directly, you may improve mental capacity. Several clinical studies showed that Acetyl L-Carnitine is a highly absorbable L-Carnitine form that can reach brain tissue and boost cognitive function.[6][7][8]

It’s also been linked to better nervous system communication and enhanced cellular energy production, which means your brain cells can become more vital and proficient.[9][10]

But Acetyl L-Carnitine isn’t the only core compound in CogniBoost. There are also two more food-based antioxidants: blueberry extract and Meriva Pythosome (turmeric extract).


The blueberry extract may help improve memory and maintain brain function. Oxidative stress can accelerate your brain’s aging process, negatively affecting brain function.

Several animal studies concluded that the antioxidants in blueberries may affect your brain areas essential for intelligence. They appear to help aging neurons, resulting in significant improvements in cell signaling.[11][12]

Human studies have also shown some promising results.

In one of these studies, a group of older adults with mild cognitive impairment was given blueberry juice daily for 12 weeks. At the end of the study, all subjects experienced increases in several markers of brain function.[13]

A six-year study in over 16,000 older individuals found that strawberries and blueberries were associated with mental aging delays by up to 2.5 years.[14]

Another interesting addition to CogniBoost is curcumin – the principal curcuminoid of the Indian spice turmeric.

People throughout Asia have benefited from the helpful effects of curcumin for hundreds of years. Curcumin is the orange pigment in turmeric (the primary ingredient in curry). It’s a substance linked with potent antioxidant properties and anti-inflammatory.[15][16]

Turmeric’s health benefits are numerous: it helps digestion of fat, maintains healthy blood sugar levels, and benefits the brain.

Curcumin has been found to support satisfaction in coping with mental strain, improve working memory, and promote calmness. It also lessens physical fatigue and promotes cardiovascular health.[17][18][19][20]

However, curcumin is hardly soluble in oily solvents or water, which results in reduced bioavailability and is generally poorly absorbed into the bloodstream.[21][22]

A potential solution to this problem comes from a patented curcumin extract – Meriva. This nutraceutical curcumin extract may offer multiple health benefits for many conditions.[23]

A 2007 single-dose pharmacokinetic animal study showed Meriva’s higher bioavailability, compared to regular curcumin extracts. The results indicated a >20-fold increase in absorption of curcumin from Meriva versus a standard curcumin preparation.[24]

You can also find curcumin in Stop Aging Now Curcumin2K.

Health Benefits

5) CogniBoost Health Benefits

CogniBoost claimed benefits include:

  • Improves short-term memory;
  • Fast-acting mental boost with all-natural ingredients;
  • Enhances cerebral blood flow;
  • Improves attention;
  • Supports healthier cognitive functionality.

6) Is CogniBoost Safe for Everyone?

As with most dietary supplements, there are risks of interaction with medications and adverse effects. People should discuss with their healthcare providers the safety of any supplement before taking it.

Potential CogniBoost side effects may include:

  • Diarrhea
  • Itching
  • Trouble sleeping (insomnia)
  • Headaches
  • Nervousness
  • Stomach upset
  • Nausea
  • Dizziness

7) What You Need to Know Before Taking CogniBoost

CogniBoost contains turmeric extract, which may slow blood clotting. Taking turmeric simultaneously with prescriptions that also slow clotting might increase the chances of bleeding and bruising.[25]

Some medications that slow blood clotting include

  • Clopidogrel (Plavix)
  • Aspirin
  • Ibuprofen (Motrin and Advil)
  • Diclofenac (Cataflam and Voltaren)
  • Dalteparin (Fragmin)
  • Naproxen (Naprosyn and Anaprox)
  • Heparin
  • Enoxaparin (Lovenox)
  • Warfarin (Coumadin)

Another ingredient known to interact with prescription medication is the American Ginseng extract. Do not take CogniBoost if under treatment with medications for depression (MAOIs), diabetes (antidiabetic drugs), or medications used to slow blood clotting like Warfarin (Coumadin).[26]

Shop For CogniBoost

8) Who Sells CogniBoost?

CogniBoost is not very popular online. It’s only available for purchase from two primary online sources: the official Dr. Sinatra website and Amazon.


9) How Much Does CogniBoost Cost?

One bottle of CogniBoost costs $29.99, but the official website offers some discount packages:

  • 1 Bottle for $29.99
  • 4 Bottles for $89.97
  • 7 Bottles for $149.95

The official website advertises the prices “with AutoDelivery.” AutoDelivery is Dr. Sinatra’s autoship program, which means you’ll get automatic repeated shipments of the product delivered to your doorstep every month. By joining this program, you can save 10% off all the retail prices listed above.

Suggested Use

10) Suggested Use

For adults, take three (3) capsules in the morning with water.

11) What Customers Say About CogniBoost

"I didn't see that it made a difference. Maybe I should have stuck with it longer, but I am inpatient and expect results within a few days." [Read full review]

---Diane M. Evans

"Great product, my entire household takes it." [Read full review]

---Jenn Lowery

"This is a great product!" [Read full review]

---Dr. Z


12) Conclusion

Clinical studies show that nootropic supplements may have a beneficial impact on your brain. But more extensive, large-scale, clinical studies are needed before scientists can fully understand how these nootropics can benefit the overall cognitive function.

CogniBoost looks like a solid formula. Acetyl L-Carnitine and Ginseng are two potent ingredients used in many brain supplements, and for good reason.

Overall, CogniBoost may benefit anyone looking for a natural brain supplement for attention, alertness, memory, and cognitive support. The reviews, while limited in number, are generally positive and the company behind this product, Dr. Sinatra, is well known for making quality products.

4.2/5 - (10 votes)

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This company took $29.90 out of my account and I’ve never heard of them. I called the # and got a call center and he said I entered this and will be charged $29.90 every month!!!!! I’m 71 yrs old on SS, I can’t afford this crap and now I have to go to the bank to stop it! Don’t do business with them, if they are so desperate as to scam the elderly they can’t be trusted!!!

Title for your comment

Has anyone lost weight on this? What are the prices like for these pills? Tell me some stuff on how it makes you feel. Does it really help with memory?

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Need info pretty please. : ) thank you in advance
Have you tried this product?
Vanessa G. Lancaster

Maybe it’s me, but after two weeks I feel no effect.

Veronica S.

I first saw this supplement last month and I was immediately attracted to it, and it’s realy helped me.

ellen proxee

My mother is having trouble swallowing the large pill. Need advice. can this be crushed or put into a liquid form. Ellen

Byron Mc
Reply to  ellen proxee

This is not a medical opinion, but I have had success with my mother by mixing the contents of the capsule into some applesauce and eating that rather than crushing or mixing with water.