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Alpha Brain Review – Is it Effective?

By Dr. Usmarah Hussain

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Nutrition Info | Claims | Adverse Effects | Contraindications | Cost | Where to Buy? | Suggested Use | Bottom Line

Alpha Brain is advertised as one of the most popular nootropics that improve mental clarity, focus level, and specific cognitive functions for peak mental performance. Manufactured by ONNIT, it is said to be a medically proven and clinically studied product for better cognition. It has been widely endorsed by famous celebrities and athletes, such as Joe Rogan. The makers of this supplement claim to have sold a million bottles to date.

This Alpha Brain review aims to explore this highly popular product in detail and analyze if it is really worth all the hype.


1) Alpha Brain at a Glance

Alpha Brain is a dietary supplement created by ONNIT with an aim to support the cognitive health of its users. It works by promoting the production of neurotransmitters and the transmission of alpha waves inside the body. Contrary to most nootropics currently available in the market, it is claimed to have strong evidence supporting its effectiveness.

Available in the form of pills and powder, Alpha Brain has been widely appreciated by celebrities. It is said to help users stay in the zone for longer and helps with the flow state to increase productivity and concentration. The product is free from dairy, gluten, and caffeine and is said to be keto-friendly.

2) The Company Behind Alpha Brain

Alpha Brain is a product of an American company called ONNIT. Founded in 2010 by Aubrey Marcus, it is located in Austin, Texas, and has over 250 employees. On its official website, ONNIT has been described as a lifestyle brand that uses a holistic philosophy called Total Human Optimization to produce products.

Since its founding, ONNIT has become an Inc. 500 company and an industry leader with over 250 products, ranging from apparel and fitness equipment to peak performance supplements and foods.

Some of their most popular supplements include Alpha Brain (the company’s flagship product), Total Gut Health, New Mood, Total Strength + Performance, Active B Complete, Key Minerals, Virutech Antioxidant Support, Stron Bone, Onnit Labs New Mood, and Shroom Tech.

Nutrition Info


3) Ingredients of Alpha Brain

According to the official website, Alpha Brain includes three types of proprietary blends, each with its own ingredients. Let’s take a look at them below:

ONNIT Flow Blend

This is used to improve alpha-brain production and includes the following:

  • L-tyrosine: An amino acid that boosts the production of neurotransmitters and improves the communication between nerve cells
  • L-theanine: An amino acid that curbs anxiety
  • Oat Straw Extract: A natural herb that improves concentration and attention
  • Phosphatidylserine: A phospholipid that increases cognition, particularly before exercise
  • Cat’s Claw: A natural chemical that improves cellular integrity

ONNIT Focus Blend

This blend aims to support focus by improving acetylcholine synthesis. It includes

  • Alpha-GPC: It supports the functioning of acetylcholine to enhance cognition and support mental performance
  • Bacopa Extract: A traditional Ayurvedic herb for improvement in cognition and memory
  • Toothed Clubmoss: It prevents the breakdown of acetylcholine to improve focus and cognition

ONNIT Fuel Blend

This blend includes ingredients to improve communication within nerves and maintain a healthy brain environment. It includes:

  • L-Leucine: An amino acid that enables the body to repair muscles and synthesize more protein
  • Pterostilbene: It possesses antioxidant properties that protect the brain from free radical damage
  • Vitamin B6: It helps with brain development and neurotransmitter synthesis

4) Alpha Brain Claims

According to the makers of Alpha Brain, this supplement can get you in the zone on a daily basis and provide the following benefits:

  • Maintain a healthy brain by protecting it from age-related damage due to the ONNIT Fuel Blend
  • Enhanced focus and ease of completing day-to-day tasks due to ONNIT Focus Blend
  • Quicker reaction times, enhanced cognition and recall, and an ability to think better under stress due to ONNIT Flow Blend

To experience the full spectrum of effects, it may take several weeks of consistent use.

Adverse Effects

5) Potential Alpha Brain Effects

Alpha Brain is generally advertised as a safe product due to its natural, chemical-free composition. However, it is always good to consult a doctor before you begin a new dietary supplement.

In rare cases, a few mild side effects may occur with the use of Alpha Brain, including headaches, nausea, gastrointestinal distress, and insomnia.


6) Alpha Brain Warnings and Precautions

Alpha Brain must not be used if:

  • You are pregnant or breastfeeding
  • You are planning to conceive in the near future
  • The seal of the products you receive is broken
  • You are below the age of 18 years
  • You suffer from any medical conditions and are taking medication for it
Where to Buy?

7) Where to Buy Alpha Brain

Alpha Brain is easily available through the company’s official website (onnit.com). Furthermore, you can also find it on Amazon and iHerb.


8) How Much Does Alpha Brain Cost?

The price per bottle for each Alpha Brain Variant, as mentioned on its official website, is as follows:

  • One bottle of Alpha Brain Original with 30 capsules is for $34.95
  • One pack of Alpha Brain Focus Shot with six servings is for $23.99
  • One bottle of Alpha Brain Black Label with 80 capsules is for $124.95
  • One pack of Alpha Brain Instant with 30 servings is for $59.95

Further discounts can be availed by ordering in bulk or subscribing to the company’s website.

Suggested Use

9) Suggested Use

Depending on the type of variant, there are two ways to consume Alpha Brain:

  • Take two capsules of Alpha Brain (original) and Alpha Brain Black Label every day with a light meal
  • Mix one pack of Alpha Brain Instant in 8 oz of cold water with a maximum dose of 2 packs a day
  • Take one bottle of Alpha Brain Focus Shot orally within 24 hours

10) Variations of Alpha Brain

The following four variants of Alpha Brain are currently available:

  • Alpha Brain Instant: A powdered supplement for better cognition and memory
  • Alpha Brain Black Label: A premium formula for extreme productivity and laser-sharp focus
  • Alpha Brain Focus Shot: A liquid variant to support energy, focus, and mood

11) What Users Are Saying

"This product is amazing. After taking two, my thoughts become clearer, and my actions seem to have more intent. I've noticed this astounding clarity. If you are a cerebral person, this product is for you. As stated in the headline, this helps my ADHD." [Read full review]

---Daniel S.

"The first dose I took made me a little queasy, and I took it with food as directed. I have been taking it for a couple of weeks now, and I no longer experience the queasiness. I feel like I do have a little more focus when I take Alpha Brain, but I'm not sure if it's as awesome as some users seem to report." [Read full review]

---Adrien Briley

"I could tell the product was working in that my concentration and attention to detail improved, though not dramatically. The con, and it is a big one, is that I developed really bad anxiety attacks a few weeks after starting on this product. After stopping the dosage, they dropped off immediately within thirty-six hours." [Read full review]

---Brian Leone

Bottom Line

12) Our Bottom Line

Alpha Brain is a nootropic supplement for an enhanced mind and brain. It has been extremely popular with its users and highly endorsed by many celebrities. The company manufacturing it is reputable, and it claims to have created this formula through rigorous research and third-party testing. Daily use of this product is expected to provide users with laser-sharp focus, clarity, and cognition.

Overall, the product seems legit and is worth a try, with the only downside of a higher cost.

4.3/5 - (3 votes)

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michelle grant

has anybody had any comments about giving this to the elderly…my dad is 93..in good health


Tip: Dont take a pre workout berofe every workout. Ive tried AMP NO LOADED and it worked best for my cardio, with it i could cardio for almost two hours. One more thing talk to people at the gym and ask what they take and if you can trade off some product so you can try other supplements, not all supplements have the same effect on everyone see what works for you.