Home » Reviews » Mood Supplements » Symphora Review

Symphora Review – 8 Facts You Need to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | Nutrition Facts | Claims | Cautions | Cost | Suggested Use | Does it Work

Symphora si presented as a dietary supplement that has been designed to support the brain cortisol function.

This is a product that has been developed and manufactured by a privately owned company called Metagenics, which was founded in 1983 in California, United States. This business soon grew past the USA borders and obtained an international status, presenting with several offices in countries like Belgium, the Netherlands, Canada, Australia and New Zealand. The team that is responsible for developing new and more effective products is involved in nutrigenetic studies, which aim to observe the influence that different nutrients have on the genetic expression within our cells.

On the manufacturer’s web site this product is said to have been created to act centrally in the brain, containing ingredients that have the ability to pass with ease through the blood-brain barrier. This formula’s main objective is to support the function of cortisol, which is one of the hormones that have been associated with well being, mood and stress response. This formula features several ingredients that are linked to mood support and combat stress on both physical and mental levels. Symphora is a formula that is recommended to be used a maximum of six months and has been designed for people that are over 18 years of age.


1) Symphora Quick Facts

Symphora sets itself in the multi-vitamin category and is made using the healing capacities of several vitamins and a hormone.

One active ingredient that can be found in Symphora is Vitamin D, a substance obtained through diet, but for the most part it is obtained through direct exposure to sunlight. This ingredient has proven its therapeutic values and was demonstrated to be effective with conditions like high cholesterol, high blood pressure, diabetes, obesity, or multiple sclerosis. Because low levels of this vitamin have been found in people that suffer for depression, a link has been observed that needs to be studies, but there are some that say this vitamin can help with mood.

DHEA is one of the other active ingredients this blend presents with and is a naturally occurring hormone in the human body. This is an ingredient that has been observed to presents with several therapeutic qualities and can be used in order to help with slowing down the effects of aging, improving thinking skills, increase muscle mass, energy, and strength. This ingredient has a role to play in the production of serotonin and thus supports a good mood, it also protects against chronic stress. Some people reported side effects like hair loss, acne, changes in menstrual cycle, or upset stomach.

Two tablets per day is the manufacturer’s recommended dosage.

Nutrition Facts

2) Symphora Nutrition Facts

Symphora contains the following ingredients: Vitamin D, Folate, Vitamin B12, DHEA, Microcrystalline cellulose, cellulose, croscarmellose sodium, stearic acid (vegetable), silica, and coating (water, hypromellose, medium chain triglycerides, and hydroxypropylcellulose).

3) Is Symphora Right for You?

This blend of ingredients is a multi-vitamin formula that contains several vitamins and a hormone.

DHEA is one of the ingredients that can be found in this product and is a hormone that is naturally made in the human body. This ingredient presents with many benefits and therapeutic uses, mainly being used to slow the effect of aging, improving thinking skills and can also increase muscle mass, strength, and energy. This substance can help with the prevention of tryptophan destruction, which is a substance that increases the production of serotonin and thus supports a better mood; it is also presented as providing protection against chronic stress, and low levels of this substance have been found in people suffering from depression. When used in appropriate doses and for short periods of time this substance is considered to be safe, but some side effect have been reported, such as acne, hair loss, changes in menstrual cycle, or an upset stomach.

Vitamin D is another active ingredient that is present in this blend and is a substance that can be obtained from certain foods, but for the most part, it is produced through direct exposure to sunlight. Over the years this ingredient has been used as to help with conditions like high blood pressure, high cholesterol, obesity, diabetes and multiple sclerosis. Low levels of this vitamin have also been found in people that suffer from depression, and there is evidence that supports the idea that this ingredient can prevent and treat depression.

The suggested use is of two tablets per day.

The manufacturer states a series of warning that regards this product; we highly advise researching these warning before a purchase.


4) What Symphora Does?

  • Every container provides a one-month supply.
  • The manufacturer has a 30-year experience in this field.


5) What You Need to Know Before Taking Symphora

  • There are several warnings regarding the use of this product.
  • Some of the ingredients used come with several side effects.
  • There are no relevant testimonials about this product’s effectiveness.


6) Symphora Cost

This product presents with just one size option, a container that holds 60 tablets that provide a one month supply at the recommended use of two tablets per day. This product falls into the expensive category of dietary health products and comes with no free trial or money back guarantee. The manufacturer supplies partner healthcare practitioners with some of their product and purchase may be available from a nearby medical doctor; direct purchase from the manufacturer’s website is also available, but only with a code that can be obtained from the same partner health care practitioners above mentioned.

Suggested Use

7) Suggested Use

The manufacturer presents a consistent list of warnings with regard to this product, a research of these warnings is highly advised prior to any use.

Does it Work

8) Bottom Line – Does It Really Work?

Symphora is a dietary health product that has the desired effect of providing mood management and also relieve stress. This product uses ingredient that help regulate the production and function of cortisol, thus supporting well being and providing a better mood. This product has been developed by a company that presents with 30 years of experience. The manufacturer presents a list of warning that should be consulted before a purchase and some ingredients presents with side effects. The price of this formula is quite high and it can be purchased directly from the manufacturer or from a number of online retailers.

4/5 - (1 vote)
Notify of
1 Comment
Inline Feedbacks
View all comments

Not so effective with anxiety, but I feel a slight improvement in general mood since I started taking it.