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Silk Fibroin Review – 6 Things To Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | Ingredients | Benefits | Warnings | Suggested Use | Conclusion

Silk Fibroin is a type of protein created by silkworms in the process of silk production. The product is manufactured by Huzhou Aotesi Biochemical, a Chinese company which claims to be a leading manufacturer of silk protein, silk amino acids, silk fibroin, silk peptide, silkworm pupa powder, distillate of male silkworm, etc in China. Also, the manufacturer claims all their products are natural green organic.

Silk emitted by the silkworm consists of two main proteins, Sericin and Fibroin. Fibroin is the structural center of the silk, and Sericin the sticky material surrounding it. There is a large applicability of Silk Fibroin, from health care food products, to liver protection from alcohol to skin and hair cosmetics.

Silk Fibroin is sold exclusively in bulk.


1) Silk Fibroin Quick Facts

Silk Fibroin contains 18 kinds of amino acids, among which we mention L-Glycine, L-Serine and L-Alanine. Amino acids are the smallest unit of proteins and are useful components in a variety of metabolism functions.

Due to its properties, Silk Fibroin has been investigated for a number of applications. For instance, Silk Fibroin films were developed for acceleration of wound healing and could be peeled off without damaging the newly formed skin. Also Silk Fibroin is considered a suitable material for skeletal tissue engineering due to its good oxygen and water-vapor permeability properties and its minimal inflammatory reaction in vivo.

Silk Fibroin research is still in its early stage, but it has been proved to improve liver function and less the drunken possibility, reduce sugar content in blood and prevent aging. Also, it is an excellent health care food additive (widely used in biscuits, candies, soybean products, noodles, ice creams, beverages) as well as a popular ingredient in cosmetics designed for the skin or for hair.


2) Details on Silk Fibroin Ingredients and Uses

Silk Fibroin includes the following ingredients: Silk Fibroin.


3) Silk Fibroin Benefits & Results

  • Wide variety of applications
  • Silk Fibroin contains 18 amino-acids, of which many essential amino-acids which regulate metabolism and other bodily functions


4) Silk Fibroin Product Warnings

  • Limited research so far on Silk Fibroin
  • The product is sold only in bulk

Suggested Use

5) Suggested Use

Silk Fibroin is sold in bulk and serves as a raw material or ingredient for other products. No side effects, precautions or other warnings are issued by the manufacturer.


6) Conclusion

Silk Fibroin is a protein made by Silkworms. It is usually used as a raw material or ingredient for various foods, dietary supplements, drinks, cosmetics or hair repair products. The manufacturer of the product reviewed sells Silk Fibroin in bulk.

Research regarding Silk Fibroin’s medical applicability is so far limited, but promising results have been obtained in areas such as diabetes, liver protection and wound healing.

It particularly has nutritional value and is used in dietary supplements because it contains amino acids which are rarely found in food (such as Serine, Alanine and Glycine, content of over 70% of the total).

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