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MSM Plus Review – 8 Facts You Need to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Ingredients | Pros & Cons | Cautions | Cost | Suggested Use | Final Thoughts

MSM Plus is marketed as a supplement that can strengthen joints and cartilage while stimulating growth and healthy connective tissues. It is recommended for people that are prone to experiencing joint pains, people that exercise a lot and need to strengthen their cartilages or people recovering from accidents, who need to re-grow connective tissue.

The company that produces MSM Plus is Lifeplus. They have over 30 years’ experience manufacturing and distributing health supplements, and put a high focus on quality, reducing their amount on advertising in order to invest in maintaining their product top-notch. They do not sell their product directly; instead, they use a pyramid marketing scheme, allowing anyone to distribute their supplements for them and recruit more sellers.


1) MSM Plus at a Glance

The formulation behind MSM Plus is an herbal-mineral one, the main ingredient being Methyl Sulfonyl Methane, shortened to MSM. The manufacturer claims that this ingredient strengthens connective tissue and is a very important element in our daily diets, but they provide no medical evidence to back up these claims. As a matter of fact, medical research conducted so far reveals that there are no medically-approved uses for this substance, and that the necessary daily amounts are covered sufficiently by a regular diet.

The proprietary blend contains a large variety of herbs, vegetables and fruit, but the use of these ingredients in the formulation is not made clear by the manufacturer, who also fails to provide medical evidence that MSM Plus performs as advertised; the only statement they make to increase the product’s credibility is that many people have tried it, and were happy with the results.


2) Details on MSM Plus Ingredients and Uses

MSM Plus contains: Methyl Sulfonyl Methane (MSM), Stearic Acid, Microcrystalline Cellulose, PhytoZyme® proprietary blend (Bromelain, Papain, Alfalfa, Parsley, and vegetable and fruit concentrates from Blueberry, Carrots, Broccoli, Spinach, Cauliflower, Kale, Asparagus, Beet, Chili Pepper, Green Bean, Pea, Sweet Potato, Cucumber, Pumpkin, Snow Pea, Tomato, Watercress, Zucchini, Lima Beans, Mushroom, Banana, Cantaloupe, Cranberry, Guava, Lemon, Mango, Orange, Papaya, Peach, Pineapple and Grapefruit), Lemon Bioflavonoids, Silica, Magnesium Stearate, and Sodium Molybdate.

3) Is MSM Plus Right for You?

MSM Plus is a source of biological sulfur aimed to promote healthy connective tissue. This mineral is needed for the manufacture of many proteins rich in sulfur-containing amino acids, including collagen, the primary protein of connective tissue, skin, hair, bones, teeth, and insulin. Sulfur is also a component of bile acids and therefore contributes to fat digestion and absorption. Animal studies using radioactive tracers show that the sulfur in MSM can even be utilized to prepare methionine. Essential proteins (insulin, human estrogen receptor, follicle-stimulating hormone, luteinizing hormone, etc.can) are dependent on sulfur.

Small-scale studies of possible treatments with MSM have been conducted on both animals and humans. These studies have suggested some benefits, particularly for treatment of osteoarthritis.

MSM is an abbreviation for Methyl-Sulfonyl-Methane. It is a natural form of sulfur found in all living organisms and is present in our body fluids and tissues. It is found in many fresh foods including most fresh fruits and vegetables, milk and some grains. Even though it is present in fresh foods, it is easily destroyed in cooking, storing and processing. MSM Plus is claimed to ensure adequate amounts of this compound are included in the user’s diet.

Take one tablet, two times per day with meals. It is suggested you begin with one 625 mg tablet twice a day and increase as desired, up to five tablets twice a day.

Pros & Cons

4) MSM Plus: Pros and Cons

  • Product suitable for vegetarians
  • Contains no artificial colors, flavors or preservatives
  • Contains no stimulants
  • Manufacturer is considered a serious name in the field of health supplements


5) What You Need to Know Before Taking MSM Plus

  • No medical evidence to support product claims
  • Purchasing directly from the manufacturer is not possible
  • Small amount of customer testimonials
  • No possibility of a free trial


6) MSM Plus Cost

Please note that this supplement can only be purchased from the manufacturer. One can either contact the company via their website or can get in touch with one of the company’s representatives. One bottle of MSM Plus contains 240 tablets, which should be enough for 60 days, depending on the dosage. Considering the average price per daily serving, this supplement is relatively inexpensive.

Suggested Use

7) Suggested Use

The dose recommended by the manufacturer for this product is one tablet, twice every day, with meals, slowly increasing it to up to five tablets a day, if necessary.

Final Thoughts

8) Final Thoughts on MSM Plus

Whether you’re an athlete, elderly person, or simply commonly experience joint pains, you know the relief that having healthy, pain-free joints can bring you. Many other people feel the same, which makes MSM Plus a considerably sought-after product, despite the apparent lack of medical evidence to attest to its efficiency.

Customer reports, though few in number, state that after taking the first 5-7 tablets, they started feeling the effects, experiencing relief in their joints and regaining some of their mobility. There are even some claims coming from athletes that say that MSM Plus helped them perform better during their training.

Lifeplus doesn’t sell their product themselves, so return policies depend on your choice of distributor. If you decide to try MSM Plus, we advise consulting a doctor beforehand, in order to prevent any negative side-effects.

3.5/5 - (2 votes)
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Randal L

At my age this formula works woders, I can still feel my bones to be strong.