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Jigsaw Health 5-HTP Review – 8 Things You Should Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | What's Inside? | Pros & Cons | Warnings | Cost | How To Take | Conclusion

Jigsaw 5-HTP is presented as being a dietary supplement that is capable of providing the body with a restful sleep, a balanced stress response and an aid for a good mood and mental emotional state.

The company that developed and manufactures this product is called Jigsaw Health and is based in the United States, being established in 2005 in Arizona. This company is said to provide its customers with premium dietary supplements that have incorporated a Sustained Release Technology, meaning a way in which the active ingredients are slowly released in the body during a long period, making the compounds more bioavailable in this way. This company places great confidence in their products, so much so that they offer a full 90-day money-back guarantee to all unsatisfied customers.

The active ingredient found in Jigsaw 5-HTP has a life spam of 90 minutes in the body, after which it rapidly disappears, giving the body just this time in order to assimilate it, but with the Sustained Release Technology, this active principle is released constantly over time, giving the body time to assimilate. Jigsaw 5-HTP is said to be an unique blend that is made with the purest form of 5-HTP that is available, this product is also free of any stimulants or preservatives and is also vegetarian friendly.


1) 5-HTP Quick Facts

Jigsaw 5-HTP is a chemical based dietary supplement that uses the healing properties that are coming from an African plant.

The base ingredient around which this product was constructed is a naturally occurring amino acid that is called 5-HTP, which stands for 5-Hydroxytryptophan and is obtained from seeds of Griffonia simplicifolia. This amino acid is said to be a chemical precursor and also a metabolic intermediate in the process that produces neurotransmitters serotonin. Consumption of this ingredient is said to provide an overall feeling of well being and to offer a healthy response to stress. Studies have indicated this chemical as having a positive effect on conditions such as depression, anxiety, premenstrual syndrome, obesity or headaches. There is contradictory information available about the effects of this amino acid, future clinical studies may assess the true effects it has. Some people have reported side effects like nausea, stomach pain, heartburn, diarrhea or sexual problems. If suffering from Down syndrome consumption of this ingredient can cause seizures so we do not recommend it.

What’s Inside?

2) What’s Inside 5-HTP?

Jigsaw 5-HTP contains the following ingredients: L-5-hydroxytryptophan (L-5-HTP from Griffonia simplicfolia seeds).

3) Is 5-HTP Right for You?

Jigsaw 5-HTP is a dietary supplement that is based on an amino acid that comes from a plant source.

The core ingredient of this formula is called 5-HTP and is a naturally occurring amino acid that is a chemical by-product of the protein building block L-typtophan, being also called 5-Hydroxytryptophan and is obtained from the seed of a plant called Griffonia simplicifolia. This ingredient is a chemical precursor and a metabolic intermediate in the production of the neurotransmitter serotonin in the body. Some evidence that comes from studies shows that this chemical can be effective with conditions like depression, anxiety, headaches, obesity, and premenstrual syndrome. This ingredient comes with some controversial information, some people claim that is unsafe and might cause severe health problems, but future studies have to be conducted in order to assess its true qualities. There are some side effects that have been linked with the use of this ingredient, such as heartburn, nausea, stomach pain, diarrhea, drowsiness, and sexual problems. Consumption is not advised when pregnant or breast feeding or for individuals suffering from Down syndrome.

There are some online testimonials about Jigsaw 5-HTP. What is being said includes the following:

  • I like it so well I’ve started my husband on it. He’s a cancer patient.

  • In the past I have taken Ambien to help me sleep but would feel tired and weak the next morning. Using the 5-HTP helps me relax to get to sleep and stay asleep the entire night. If I use another brand of HTP, I go to sleep but cannot sleep through the night.

Pros & Cons

4) 5-HTP: Pros and Cons

  • This product is said to be vegan safe.
  • A full 90-day money-back guarantee is available.
  • Free shipping is available for orders over $89.
  • One bottle is enough for two months of use.


5) 5-HTP Product Warnings

  • The core ingredient is not yet full understood and contradictory information is found.
  • There are no free trials associated with this formula.
  • Although there are a number of customer testimonials, no information regarding a long-term use is available.


6) How Much Does 5-HTP Cost?

This formula comes in the form of a bottle that provides 120 tablets per container and these last for about two months. The manufacturer offers direct purchase for all their products via their web site; a number of advantages are also present, such as a full, 90-day money-back guarantee that comes with all their formula, free shipping for orders that are over $89, and a number of price reductions if several bottles of the same product are purchased. The manufacturer recommends a dose of one or two tablets per day taken with or without food, or as indicated by a healthcare practitioner after a consult.

How To Take

7) How to Take 5-HTP

One bottle of formula is said to provide a two month supply and holds 120 tables per container. The manufacturer recommends a daily dosage of two vegetarian tables that are to be taken with a meal.


8) Conclusion

Jigsaw 5-HTP seems as a potent dietary supplement, but is in the need of some more studies in order to truly assess the implications of it use because of its main ingredient. This product is available at an affordable price, about 17 dollars for a month’s supply and comes with a full 90-day money-back guarantee that is available for unhappy customers. The manufacturer makes this product available on their web site and also offers a series of price discounts depending on the amount purchased. All the ingredients used in this blend are said to be vegetarian friendly, and the and product is presented as being vegan safe and with no preservatives or artificial colors in its blend.

3.7/5 - (3 votes)
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This formula helps me relax and provides a long restful sleep.

Roberta D

This is the only 5-HTP product that gets me to sleep at night.