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Calotren Advanced Review – 8 Essential Things to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Ingredients | Is it Safe? | Cost | Suggested Use | Bottom Line

Calotren Advanced is advertised as a protein-enzyme complex designed to increase metabolism, promote weight loss, and help repair and rebuild lean muscle. It is distributed by Top of The World USA.

Calotren Advanced contains collagen and a digestive enzyme that allows the body absorb the collagen protein up to 3x faster.

Calotren’s distributor claims that Calotren can reduce overall weight, maintain a normal weight, improve joint health, and cause better sleeping patterns.

Are these claims valid? Does Calotren really work? Keep reading this article to find out.


1) Details on Calotren Advanced Ingredients and Uses

Calotren contains Collagen Hydrolysate and ProHydrolase

Collagen is the dominant protein in the human body and has many functions. It makes up thirty percent of body tissue and seventy percent of skin tissue. It is commonly referred to as the body’s ‘glue’ and is found in connective tissues in bone marrow, tendons, cartilage, ligaments, and linings of body organs.

Collagen Hydrolysate is a form of Collagen that has been broken down into individual amino acids that are easier for the body to absorb.
Collagen helps repair tissue, maintain skin structure and elasticity, reinforces bone structure, and supports joint structure and integrity.

ProHydrolase is a scientifically engineered blend of enzymes designed to efficiently help your body break down proteins into amino acids and increase or potentiate the uptake of these amino acids.

2) What Does Calotren Advanced Do?

Calotren via its ingredients helps

  • Prevent the loss of lean muscle mass by boosting collagen levels

  • Enhance weight loss by increasing the body’s metabolism and fat burning

  • Maintain a healthy weight in users

  • Improve joint health

  • Improve digestion

  • Enhance sleep quality

Is it Safe?

3) Calotren Advanced – Is it Safe?

Calotren is generally safe when taken as recommended.

Where to Buy?

4) Where to Buy Calotren Advanced?

You can buy Calotren directly from the distributor’s website.


5) Calotren Advanced Cost

A month’s supply of Calotren costs $72.95 with discounts available on larger purchases.

Suggested Use

6) Suggested Use

Take four Calotren capsules at bedtime on an empty stomach (2-3 hours after your last meal) with a glass of water.

7) Variations of Calotren Advanced

Calotren is also available in liquid and powder formulations.

Bottom Line

8) The Bottom Line – “Does it Work?”

Calotren is based on two active substances, collagen, and a digestive enzyme, that work together to increase metabolism and improve weight loss. Calotren can also reduce joint pain and improve joint flexibility, sleep quality, and digestion.

Although Calotren can help you lose weight, note that it is not a miracle weight-loss supplement and should be combined with a healthy diet and exercise plan to achieve maximum results.

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