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BioSom Review – 8 Things You Didn’t Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Facts | What's Inside? | Claims | Precautions | Cost | How To Take | Verdict

BioSom is promoted as an easy-to-use form of DHEA advertised as beneficial on multiple levels for the overall health. The formula is created and marketed by Metagenics, a company specialized in creating formulations that aim to treat chronic conditions. The manufacturer offers various therapeutic lifestyle change (TLC) programs that have allegedly helped thousands of people in reducing symptoms of common chronic illnesses (high blood pressure, diabetes, obesity or heart disease).

This product is based on the endogenous steroid hormone Dehydroepiandrosterone (DHEA), naturally produced by the adrenal glands, brain, and gonads. The formulation is advertised to be beneficial in promoting healthy DHEA and DHEA sulfate levels for normal adrenal function, in promoting healthy sexual function (by modulating metabolism of androgens), mood, bone mass and immune function, and generally supporting the general well-being of its consumers. The supplement features 3 active compounds: two herbal extracts: Stevia Leaf Extract (Stevia rebaudiana) and Grapefruit Seed Extract (Citricidal), and DHEA (Dehydroepiandrosterone). The formula may help alleviate depression symptoms which may be liked to low DHEA levels (particularly in people over the age of 40).

The liquid form of this product makes it particularly useful for individuals who have difficulty in swallowing capsules or tablets. BioSom is designed only for the use of adults over 18 years old. Special precautions should be taken by people who are already under medication or suffer from particular health conditions indicated by the manufacturer on the official web-page.


1) BioSom Quick Facts

BioSom ingredients include 2 herbal extracts and the steroid hormone DHEA.
DHEA hormone is the most abundant circulating steroid in humans. Its main functions are in mediating metabolic processes and in the synthesis of the male and female sex steroids (androgen and estrogen). The compound has also been research in the treatment of memory impairment, female fertility, lupus, and cardiovascular disease. DHEA supplement have also been used to enhance immunity and reverse some of the aging effects or increase strength (muscle mass). Studies have failed to support any of the health benefits mentioned above. Although these studies did not reveal any dangerous adverse reactions, the long-term side effects for the use of DHEA supplements are unknown. Mild side effects include headaches, insomnia, fatigue, mood changes. Physical changes may also occur in both men (more breast tissue) and women (facial hair, deeper voice). Some research suggest that this type of supplementation my increase the risk of certain cancers affected by hormones and interact with other medication (blood thinners, medication for liver, heart or diabetes and hormone based therapeutic drugs).

Stevia Leaf Extract (Stevia rebaudiana) is a plant used particularly for its sweet taste in the food industry. The medical uses of this plant are in weight loss, diabetes, and high blood pressure treatments, preventing pregnancy. Studies have not managed to reach a common ground regarding the effectiveness of this plant in any of the health claims. More evidence is needed in order to recommend this extract as an alternative treatment for such conditions. Common side effects experienced by consumers are bloating, dizziness, numbness, and muscle pain. Those with known allergies to ragweed plants should also be aware of such a reaction when taking a stevia-based supplement.

BioSom side effects consist of acne, hair loss, aggressiveness, irritability, and increased levels of estrogen. More serious side effects like rapid heart-beat, blurred vision, and dizziness require the immediate attention of a healthcare specialist.

What’s Inside?

2) What’s Inside BioSom?

BioSom contains the following ingredients: Stevia Leaf Extract (Stevia rebaudiana), Grapefruit Seed Extract (Citricidal), DHEA (Dehydroepiandrosterone), purified water, castor oil, Polysorbate 60, natural flavors, Benzyl Alcohol, Sorbitan Stearate, Potassium Sorbate (as preservative), lecithin (soy), xanthan gum, and disodium EDTA (preservative)

3) Is BioSom Right for You?

BioSom ingredients are combined in a mixture of a hormone and two botanical extracts. According to the manufacturer, DHEA (also known as the anti-aging hormone) can regulate essential hormones that the body produces in a natural matter and plays a vital role in increasing lean muscle mass, burning fat, and stimulating bone growth. Important functions of the chemical revolve around mood regulation and ensuring the well-being of the consumer.

Stevia Leaf Extract (Stevia rebaudiana), is an incredibly sweet, low-calorie dietary supplement that has been used for more than 1.000 years by the Gurani Indians of Paraguay. The herb is currently utilized in some South American countries to assist diabetics and the hypoglycemic. Stevia has been initially used as a digestive aid and to treat obesity, but some recent studies have shown the plant to be useful in treating people with hypoglycemia and diabetes.

DHEA is a substance that is produced by the body in abundant supplies during youth, reaching a peak around age twenty-five. Low levels of DHEA are usually caused by stress and some clinicians monitor DHEA levels to track long-term stress. DHEA levels are also reduced by alcohol and caffeine (from coffee, tea, sodas, chocolate, candy, medications, etc.) consumption.

Bosom side effects may occur if the recommended daily dose is exceeded. The list of possible side effects includes hair loss, irritability, increased estrogen levels and facial hair in women.

BioSom is sold as a liquid spray that should be taken directly under the tongue and held there for about 20 seconds. The spray can be applied under the tongue up to four times per day. According to the producing company, following this treatment can lead to a substantial boost to the immune system. However, there is no data offered on the website to support these statements and to prove how this particular formula can improve mood and the overall well-being.


4) What BioSom Does?

  • BioSom is a liquid formula (which eliminate the risk of not being used by consumers with difficulties in swallowing pills)
  • The formula is described in detail by the manufacturer
  • Sufficient information can be found about each of the active ingredients
  • The monthly price is reasonable (approximately $17)
  • Unopened products are refundable if returned within 30 days from purchase
  • You can buy BioSom at affordable priced, from numerous online and offline retailers.


5) Precautions of BioSom Use

  • The formula is not clinically tested
  • Although mostly positive, Biosom reviews from consumers are reduced in number
  • There is no mentioning of a free sample (the product can normally be purchased only from the healthcare practitioner’s office)


6) How Much Does BioSom Cost?

The formula is a relatively cheap product if we are to compare it to other forms of DHA. You can buy BioSom from both online and offline retailers. One unit of this product should be enough for about one month of treatment. Health insurance plans may cover the cost for this product; however, you should further inquire on the matter with your healthcare practitioner.

How To Take

7) How to Take BioSom

BioSom reviews are generally positive, although in e relatively low number. The suggested dose is one serving one to four times daily in divided doses.


8) Our Final Take On BioSom

BioSom formula is a nutritional supplement offered for the improvement of the overall health, with particular advertised benefits on the adrenal and sexual functions. The product is not indicated for people suffering from heart disease, prostate enlargement, prostate cancer, low “good” cholesterol, or individuals who are already under medication without first consulting a physician. The manufacturer also warns against the use of this formula by pregnant and nursing women. The recommended dose should not be exceeded because of a potential risk of serious adverse health effects. A bottle contains approximately 85 servings (sufficient for a month’s supply at a moderate dose of 3 servings/day).

The formulation may however cause unwanted effects even when the suggested dose is complied with. These reactions derive from those of the active substances and should be taken seriously by those who experience any of the listed symptoms. The best approach when using unapproved dietary supplements is asking a specialized advice prior starting its administration.

4.5/5 - (2 votes)
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I trust Metagenics products, having already used BeneSom and a couple of other formulas. This BioSom formula I take to enhance my lately rather depressed mood, and I find that it is easy to use, and effective at the same time. I am easily able to find a sense of calmness and well-being and it’s something I owe to this formula

Reply to  rose

Hi Rose. How long did it take to to get results for depression? I am in post menopause and my dheamlevels and testosterone very low. Thank you
How much do you take daily

Jason mkindle

I was recommended this for my adrenal fatigue. And while it is fairly easy to use and rather heap, I really cannot say how much it works. I have been using this for several weeks now, and I do feel some positive improvement but not as much as I would have expected. I will keep you posted on the results!