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Puritan’s Pride Puritan’s Pride DMAE Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Overview | Nutrition Facts | Claims | Precautions | Cost | Directions | Final Thoughts

Puritan’s PrideDMAE is designed to provide the neuro-precursor DMAE (dimethylaminoethanol or dimethylethanolamine), an organic compound which promotes brain function.

The company behind the product is called Puritan’s Pride, and is a business that enjoys more than 40 years of experience on the dietary supplements market.

The manufacturer formulates and markets different supplements that include herbal extracts, multivitamin formulations, sports nutrition, health and beauty products and amino-acid based dietary supplements. They’re the same company behind nootropics like Calm Tabs.

The company is established in Long Island, New York, United States but they also have numerous production facilities located throughout the U.S.A.

According to the manufacturer’s statements, this product is was specially developed to improve concentration, vigilance and alertness. The formula is recommended for people over the age of 18, and for individuals who feel like their mental abilities and clarity have altered over time. The blend does not include artificial color, flavor or sweetener, preservatives, sugar, starch, milk, lactose, soy, gluten, wheat, yeast, fish or sodium. Unfortunately, there is little information about the product on the manufacturer’s website, which could be a problem for consumers.

Precautionary measures should be taken before using DMAE if you have, or have had, a health condition or you are currently taking any medications or remedies, including OTC medications.


1) Quick Overview

The key ingredient in this formulation is DMAE, which as stated above, is a natural metabolite in the body. This compound is related to the B factor choline and is known as a precursor to Acetylcholine. Although DMAE itself has not been reviewed by clinical trials, DMAE is the subject of research, mostly in short-term studies that have shown an increase in alertness and vigilance. The chemical has also shown a positive influence on mood especially if combined with vitamins and minerals. DMAE is not able to cross the blood brain barrier, hence its use as a brain enhancer may raise some amount of controversy, unless other chemicals able to help it cross the BBB are present in the supplement.

Several studies demonstrated that DMAE may be therapeutically valuable in the treatment of ADHD (attention deficit hyperactivity disorder). However, the results are not conclusive and additional research is needed to fully support this claim. DMAE is known to be relatively safe, but there may appear some mild side-effects. The recommended daily serving is one capsule, preferably taken with a meal. The product is not recommended for pregnant women or nursing. You should keep in mind that the dose should not be exceeded, as it may cause adverse effects.

Nutrition Facts

2) Puritan’s Pride DMAE Nutrition Facts

DMAE contains the following ingredients: DMAE, Cellulose (Plant Origin), Gelatin, Silica, and Vegetable Magnesium Stearate.

3) Does Puritan’s Pride DMAE Work?

As stated above, DMAE is a natural metabolite in the body. This element is related to the B factor choline and is a precursor to acetylcholine.

While there is little information available about this particular supplement, DMAE was involved in several short-term studies that have shown an increase in alertness and vigilance with a positive influence on mood following administration of this substances. It is also important to understand that in these studies DMAE was combined with vitamins and minerals.

Research for ADHD (attention deficit hyperactivity disorder) has also been promising. However, the results are far from conclusive, and additional research is required in this area.

DMAE should be relatively safe to use with very few reported side effects. The recommended dose is one capsule daily, preferably with a meal. Women who are pregnant or nursing should avoid this supplement. It is never advised to exceed the maximum recommended dose. Excessive intake may cause adverse reactions.

Unfortunately, there are very few testimonials about this product. The general tendency appears to be slightly negative with many consumers reporting just small improvements.


4) Puritan’s Pride DMAE Claims

  • Each bottle contains 100 capsules, which should be enough for 3 months of treatment for the average user.
  • The company will offer you various discounts, free bottles and free shipping, depending on your order.

5) Precautions of Puritan’s Pride DMAE Use

  • There is little information about DMAE.
  • The product has not been reviewed by the FDA.
  • DMAE has been involved in a limited number of clinical trials

6) How Much Does Puritan’s Pride DMAE Cost?

The average price per capsule is what makes DMAE a excellent deal. This supplement is one of the cheapest DMAE products available on the market.

Each bottle contains 100 capsules, which should be enough for three months of treatment for the average user. The product can be purchased directly from the manufacturer. If you choose to do that, the company will offer you various discounts, free bottles, and free shipping, depending on your order.


7) Directions For Taking Puritan’s Pride DMAE

There is a small number of testimonials on DMAE, but the majority of them are negative, with just a few reports of small improvements.

Final Thoughts

8) Final Thoughts on Puritan’s Pride DMAE

DMAE is a supplement designed for improving certain mental abilities, such as concentration, vigilance and alertness. There are numerous supplements similar to this, which is why you should investigate the market before deciding to purchase. Although the main ingredient, DMAE is rather popular for its benefits related to brain, this particular product’s effectiveness has not been proved by any kind of trials. However, the fact that the formula is relatively cheap compared to others may be a significantadvantage. You should always consult a healthcare practitioner before the consumption of any dietary supplements.

4.3/5 - (3 votes)
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We haven’t used this product too long but my wife is having a lot of Brain health issues and we want to do everything we can for her health. Even if you are not having known problems it is still good to focus on brain health. Good value and quality appearance.

Frank Hopkins

I have experienced for the longest time difficulty in having a clear mind when waking up. Ever since I started taking DMAE, it\’s like someone turned the lights on in my brain, after I take it as soon as I wake up. I recommend it for those who have a fuzzy mind when rising.

G. Ellen

I am so far greatly enjoying this study and concentration aid. It smooths out the sometimes-blurred edges of daily life and provides sharper focus and strengthened stamina when it comes to studying for long lengths of time.