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Pure Science Supplements L-Carnitine Review – 8 Reasons To Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Nutrition Info | Benefits | Contraindications | Cost | Directions | Bottom Line

L-Carnitine is a multi-targeted supplement designed to support cognitive function, promote optimal energy levels and normal weight in those who chose to use it. The formula is created by Pure Science Supplements, a company that commercializes numerous other nutraceuticals. An official site doesn’t exist at this time, so information about the company’s activity, headquarters, history, and complete range of products does not exist.

This formula is claimed as a highly effective and able to cross the blood brain barrier where the active substance, L-Carnitine is actually needed. The product is marketed as produced in a GMP facility, like all Pure Science Supplements products.


1) What is L-Carnitine?

This single ingredient formula is based on a naturally occurring amino-acid (non-essential) within the human body called Carnitine. Over 90% of the total amount is found in the skeletal muscles, but the brain and heart also need Carnitine to function properly. The compound is a popular ingredient in sports nutrition and weight loss products. Its main function is to transport fatty acids within the mitochondria where it is further transformed into energy. This is why athletes and physically active individuals, with higher energy demands, commonly use Carnitine based supplements.

At this time there are numerous forms of supplemental Carnitine, not all equally effective. One of the most potent forms is considered to be Acetyl-L Carnitine. This form acts as a precursor to the important neurotransmitter Acetylcholine, a chemical responsible for interneuronal communication. Acetylcholine is considered a key nutrient in the brain, its presence in normal amounts being directly related to the maintenance of memory, alertness, and learning capabilities. The L-Tartrate form provided by this supplement has been shown to improve muscle recovery and reduce muscle damage caused by sustained physical exercise.

L-Carnitine brain benefits result from its capacity to prevent age-related memory decline and reduce stress levels. This made scientists test the chemical as a potential solution against Alzheimer’s disease, a neurodegenerative condition for which there is no viable treatment at this time.

Nutrition Info

2) Ingredients of L-Carnitine

L-Carnitine contains the following ingredients: L-Carnitine contains the following ingredients: L-Carnitine (as L-Tartrate) – 500 mg

3) Is L-Carnitine Right for You?

Carnitine, the single active ingredient in this formula is a naturally occurring amino-acid synthesized from two other amino-acids, Lysine and Methionine in the liver and kidneys. The largest concentrations of Carnitine are in the body’s most metabolic organs: muscles, brain, and heart. The main function accomplished by this key substance is transportation of fatty acids into the mitochondria which transforms them into energy. Age and disease are the main causes of Carnitine depletion. When the reserves of this compound are low we experience feelings of constant tiredness and helplessness. At the same time muscle mass decreases and body fat increases. Carnitine supplementation becomes mandatory for people interested in maintaining muscle mass, and those who want to remain active and enjoy the benefits of having the energy to perform daily tasks.

Studies involving elderly subjects who were given L-Carnitine supplements revealed very positive results. Not only did the muscle mass increased by noticeable levels (along with a decrease in body fat), but their mental and physical endurance also improved. Investigations also showed that Carnitine also offers a potent cardiovascular support and that it can prevent and reduce symptoms of angina and ventricular arrhythmia, and even prevent death caused by cardiovascular disease. A form of Carnitine containing the Acetyl group (Acetyl-L-Carnitine) has been studied for its potential benefits in reducing Alzheimer’s progression and preventing memory degeneration. So far results look promising, but more research is needed.


4) L-Carnitine Benefits & Results

  • The formula is based on a single active ingredient (which eliminates the possibility of active substances interactions).
  • L-Carnitine can be purchased at discounted prices for as low as $20 (based on offers found at the time of this review).


5) L-Carnitine Warnings and Precautions

  • We couldn’t find the producer’s official site.
  • The amount of active substance provided by the formula is moderately low (usually, a minimum daily dose of 1g is considered effective). At a dosage of 1 capsule per day of L-Carnitine you will only get 500 mg of L-Carnitine.


6) L-Carnitine Cost

L-Carnitine is available on Amazon.com and is on discount right now. The price for a month supply is only $15.70 (reduced from the standard price of $29.70). Other retailers sell the formula, but you should be careful where you purchase it as some retailers don’t offer discounts.


7) L-Carnitine Directions

Carnitine side effects include nausea, stomach upset, vomiting or diarrhea, or high blood pressure. These are the most common unwanted reactions that occur when excess doses are taken. An optimal dose for increasing muscle mass is 1 to 3 g of supplemental Carnitine per day. The recommendations may differ depending on the purpose of usage.

Bottom Line

8) The Bottom Line – “Does it Work?”

L-Carnitine appears to be a potent and balanced product. The benefits of Carnitine supplements have been well-documented and at this time it is used as a line of treatment for circulatory system conditions, age related memory problems, type II diabetes, immune system deficiencies, and male infertility. Although in some of the cases, scientists are still conducting studies, the compound was demonstrated as generally beneficial for human health.

This formula provides a daily dose of only 500 mg which is a little bit low if we take into considerations the recommendations of the nutritionists. However, consumers who tested the product are generally satisfied with its effectiveness, and that is what is more important in the end. A money-back guarantee is also available as a backup solution for those who will not be satisfied with the product.

3/5 - (1 vote)
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