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PS 100 Review – 9 Essential Things to Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Overview | Ingredients | Adverse Effects | Price | Directions | Conclusion

PS 100 by Pure Encapsulations is a dietary supplement designed to promote brain function by increasing levels of Phosphatidylserine. Phosphatidylserine acts by increasing cellular communication and supports the optimal fluidity of the neuronal membrane.

PS 100 contains a standardized extract of Phosphatidylserine, supporting mental performance, cognition, and mental acuity.

This review looks at PS 100’s uses and benefits, allergies and side effects, and if it’s worth the buy at all. Keep reading to find out more.


1) Quick Overview

Phosphatidylserine is a phospholipid found in all cell membranes and in the myelin sheath of axons. Its use has been linked to beneficial effects on reducing the risk of dementia and cognitive decline; however, studies are limited.

Supplemental Phosphatidylserine was initially derived from animals but was associated with an increased risk of contracting zoonotic pathogens.

According to the manufacturer, PS 100 contains a high concentration of soy-based Phosphatidylserine, providing as much as 100mg of pure Phosphatidylserine in just one capsule.

2) Who Makes PS 100

Pure Encapsulations, a US-based company, makes PS 100.

Pure Encapsulations manufactures hypo-allergenic supplements, free of artificial flavors or other preservatives that could interfere with the effectiveness of their products.


3) PS 100 Ingredients

PS 100 contains 100mg Phosphatidylserine.

Phosphatidylserine is a phospholipid, a substance made up of Phosphate, fatty acid derivatives, and glycerol. It is a core component of cell membrane structure and forms part of the myelin sheath, which protects your nerves.

PS 100’s significant benefits through Phosphatidylserine are discussed below.

4) What Does PS 100 Do?

PS 100’s formula is based on just one active ingredient: Phosphatidylserine.

  • Phosphatidylserine is a vital component of the myelin sheath. This layer wraps around the axons of neurons to help protect them and increase the frequency and speed of electrical communication between them. The myelin sheath helps more information travel faster and further between neurons.

  • Low levels of Phosphatidylserine have been associated with depression and impaired mental function, including memory and cognition. PS 100 can boost Phosphatidylserine levels, prevent or slow the progression of these diseases, and reduce the risk of dementia in the elderly.

Overall, PS 100 can improve brain health and support cognitive function, emotional well-being, and memory.

Adverse Effects

5) Potential PS 100 Adverse Effects

PS 100’s primary ingredient is a Phosphatidylserine derived from soy. Consumption of soy derivatives may cause allergic reactions in people who are allergic to soy.

Where to Buy?

6) Where to Buy PS 100?

You can buy PS 100 directly from the Pure Encapsulations website or select online retailers like Amazon and iHerb.


7) PS 100 Price

It costs $69.80 for 60 capsules of PS 100.


8) PS 100 Directions

Take one capsule of PS 100 three times daily with meals.


9) Conclusion

If you’re considering using a Phosphatidylserine supplement, PS 100 is a good source of supplemental Phosphatidylserine and has positive testimonials from consumers regarding its effectiveness in improving memory, boosting energy, and enhancing mood.

Although little known research is linked explicitly to PS 100 itself, its active ingredient, Phosphatidylserine, has been involved in various clinical trials, with positive results on cognitive, behavioral, and memory-related aspects; However, as with all supplements, please note that results may vary by individual.

4/5 - (8 votes)
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I used to have moments in a day in which I could not focus my attention on anything, this nearly cost me my job so I decided to find a solution. My brother suggested I should use this formula and it works wonders.

James H

Before using this formula I used to be a fan of herbal supplements, but this one convinced me that there are no rules in regard of dietary supplements. The thing that caught my attention is that the active ingredient is naturally found in the body. This formula really helped me with my focus and I now have a better memory as well.