Home » Reviews » Other » OPC Synergy Review

OPC Synergy Review – 8 Things You Should Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Ingredients | Health Benefits | Price | Where to Buy? | Suggested Use | Conclusion

OPC Synergy is a dietary supplement advertised to provide a synergistic blend of antioxidants designed to support cell functioning.

The formula is offered by Standard Process, an experienced manufacturer of dietary supplements, which claims the product’s core benefits include support for normal cell functioning, eye health, cardiovascular system, and the complex processes associated with aging.

The formula is said to contain Oligomeric Proanthocyanidins, one of the most potent antioxidants known today. They are claimed to be much more effective than Vitamin C and boost overall body health.

Are these claims valid? Does OPC Synergy actually work? Read this OPC Synergy Review to find out all about it.


1) OPC Synergy at a Glance

OPC Synergy features extracts of plants and seeds with powerful antioxidant properties.

The Grape Seed Extract featured by the formula is claimed to contain OPCs, a group of substances considered one of the most potent free radical scavengers ever discovered. Extensively researched, the nutrient is now officially recognized as “Vitamin P.”

OPCs, commonly derived from a combination of red wine extract, grape seed extract, and/or pine bark extract, have been scientifically demonstrated to be 20 times more effective than Vitamin C and 50 times more effective than Vitamin E as a free radical scavenger. OPCs are shown to cross the blood-brain barrier and improve brain tissue oxygenation. They are currently researched for potential benefits in Attention Deficit Hyperactivity Disorder and Attention Deficit Disorder.

Several animal studies show OPCs may improve memory associated with age-related cognitive decline. Animals receiving OPCs for five weeks showed improved spatial and object recognition.

Clinical testing and scientific research in humans reveal no evidence for allergic reactions, toxicity, or carcinogenicity. OPC is 100% bioavailable in humans, remaining in the body for up to 72 hours.

2) The Company Behind OPC Synergy

Standard Process is a U.S.-based company founded more than 80 years ago.

The company manufactures and markets over 300 products including veterinary formulas, whole food supplements, and herbal supplements.

According to the company, the entire range of products is compliant with the Good Manufacturing Practice (GMP) requirements set forth by the Food and Drug Administration.

Popular supplements by Standard Process include Bacopa Complex, Ashwagandha Complex, Collagen-C, and Congaplex.


3) Details on OPC Synergy Ingredients and Uses

Each Serving Size (1 Capsule) of OPC Synergy contains

Proprietary Blend 410 mg: Organic buckwheat (aerial parts) juice powder, organic buckwheat (aerial parts), green tea (leaf) powder, organic carrot, grape seed extract, bilberry (fruit) extract, green tea (leaf) extract, and red wine extract.

Grape Seed is rich in potent antioxidants, including Oligomeric Proanthocyanidin Complexes, also known as OPCs. Grape seed extract has been used to lower blood pressure, improve blood flow, fight inflammation, and reduce oxidative damage to body cells and tissues.

Red wine extract is obtained from the fermentation of grapes. Red wine extract contains high levels of resveratrol, a potent antioxidant, and many other antioxidants.

Green Tea Extract is obtained from the leaves of Camellia sinensis. It originates in China and has become associated with several cultures from Asia. According to some studies developed in the United States, the main active ingredients in green tea are flavonoids, and the concentration is higher than the same volume of other drink or food items, such as wine or vegetable juice.

Green Tea extract has a wide spectrum of medical applications. It contains caffeine, antioxidants, and polyphenols which include flavonoids. Polyphenols help with Dopamine synthesis, an important neurotransmitter that regulates mood, motivation, decision making, and attention.

Flavonoids represent a group of phytochemicals that are responsible for anticarcinogenic and antioxidant functions.

Green tea extract is believed to assist with conditions ranging from Chronic Fatigue Syndrome and Parkinson’s disease to blood pressure and certain types of cancer.

Another compound in this supplement is Bilberry, also known as Vaccinium myrtillus. As an ingredient of natural remedies, bilberry has been used as a blood strengthener and sight improver and can prove reliable in treating macular degeneration, cataracts, and diabetic retinopathy. It is regarded as likely safe when consumed in food amounts.

4) What Does OPC Synergy Do?

Providing a natural answer when it comes to treating symptoms of mental disorders or just helping with the proper development of the immune and cardiovascular system, OPC Synergy contains four herbal extracts with antioxidant properties.

Overall, OPC Synergy

  • Boosts the body’s antioxidant levels
  • Helps maintain a healthy cardiovascular system
  • Improves eye health
  • Sustains normal cellular functions
  • Supports capillary wall integrity
  • Supports normal cognitive functions
Where to Buy?

5) Where to Buy OPC Synergy

You can buy OPC Synergy from various distributors accessible via the company website or online retailers like Amazon.


6) OPC Synergy Price

OPC Synergy is sold in bottles containing 40 capsules and generally costs $51.46 for 40 capsules. A bottle is usually enough for 40 days of use.

Its price may vary by retailer, but it’s considered to be moderate, especially compared to similar supplements. You may be able to purchase this product at lower prices by ordering larger amounts and combining other discounts or promotions provided by the retailer.

Suggested Use

7) Suggested Use

Take one capsule of OPC Synergy daily, or take it as directed by your physician.


8) Conclusion

OPCs have been used for several decades and have been investigated for their numerous potential benefits. They are known to be potent free radical scavengers, collagen binders, and inhibitors of histamine formation and inflammatory enzymes, to name their most essential functions.

OPC Synergy has been manufactured for more than ten years. Although the number of consumer reviews is limited, those available lead us to assume that the formula will achieve its benefits considering the manufacturer’s excellent reputation and the extended availability of the product on the market.

Nevertheless, we recommend you talk to a healthcare provider before using OPC Synergy and advise that this supplement is not intended to diagnose or cure any medical illnesses.

3.3/5 - (6 votes)
Notify of
1 Comment
Inline Feedbacks
View all comments
Homer L. Jackson

At first I thought this product was good only for improving the sight, but man was I wrong! It helps with everything, from the heart to the lungs and the brain. It’s the best supplement I’ve ever come across in my life. Totally worth my money