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CholestOff Complete Review – 9 Facts You Need to Know

By Dr. Usmarah Hussain

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Synopsis | Nutrition Info | Contraindications | Cost | Where to Buy? | Directions | Bottom Line

A huge chunk of the population continues to suffer from high cholesterol due to unhealthy dietary habits and a sedentary lifestyle. Medically known as hypercholesterolemia, this disease is dangerous and poses a serious risk to the heart and brain health. While multiple pharmaceutical interventions are available to tackle the rising cholesterol levels, they often come with various side effects. These side effects eventually compel patients to start looking for more natural alternatives, one of which is CholestOff.

Manufactured by Nature Made, a popular company with more than 200 supplements under its brand name, CholestOff has been advertised as a vitamin and herb-based dietary supplement to naturally suppress the increasing cholesterol levels. Can this supplement truly replace the pharmaceutical cholesterol-lowering medications? How much does it cost, and what do the reviews say? Keep reading to get all these queries answered.


1) CholestOff Complete at a Glance

Maintaining healthy cholesterol levels is extremely important for good heart health. CholestOff by Nature Made is a natural supplement designed to take care of your heart by regulating the rising cholesterol levels in the body. It combines different ingredients, such as Pantesin and Reducol to stop the production of cholesterol in the liver while minimizing the risk of heart disease. Other ingredients included in this supplement include an amalgam of stanols and sterols extracted from pine trees that lower the risk of hypercholesterolemia due to genetic and environmental factors.

Available in the form of easy-to-use soft gels, CholestOff is easy to incorporate into daily life and is claimed to benefit the body without triggering any side effects. However, it is important to keep in mind that these claimed statements are yet to be evaluated by the Food and Drug Administration. Moreover, the product is not meant to treat or cure any medical condition and must not be used as a replacement for any pharmaceutical drug without consulting a doctor first.

2) The Company Behind CholestOff Complete

Nature Made is a company dealing with products related to health and wellness since 1971. It was founded by Henry Burdick and Barry Pressman, who envisioned a better alternative to longer, better health than prescription medication. It aims to go the extra mile to ensure that its supplements are of the highest quality, verified by the USP, and tested thoroughly for potency and purity by the U.S. Pharmacopeia.

The company manufactures all of its products, including the CholestOff, in high-tech facilities and under the care of a highly qualified supervision team. The core members of this team include a Naturopathic doctor, PhD-holder staff, and registered dieticians. Each of its products is backed by over 35 years of experience, research, and science and is made to fit the lifestyle of its users at every stage.

Nutrition Info

3) Ingredients of CholestOff Complete

The active ingredients of CholestOff have been sourced from natural plants, including pine trees. These include:

  • Reducol, a patented blend of plant stanols and sterols, that works to reduce the absorption of cholesterol coming through diet into the bloodstream
  • Pantesin slows down and potentially limits the production of cholesterol in the liver

According to the manufacturing company, four capsules of CholestOff deliver up to 1.8 grams of stanols and sterols to regulate blood cholesterol. These capsules are free from gluten, yeast, artificial flavors, and preservatives. Besides plant sterols and stanols, other ingredients of this supplement include:

  • Cellulose Gel
  • Polyethylene Glycol
  • Calcium Carbonate
  • Triethyl Citrate
  • Polysorbate 80
  • Tribasic Calcium Phosphate
  • Silicon Dioxide
  • Hydroxypropyl Methylcellulose
  • Croscarmellose Sodium

4) Does CholestOff Complete Work?

Several research studies have been performed to test the efficacy and claims put forth by CholestOff and some of it support its ability to reduce blood cholesterol levels. The supplement is loaded with plant stanols and sterols that have been proven to reduce total blood cholesterol by 2.8% and LDL cholesterol by 4.9%

Many independently working websites, such as Amazon, also have many customer reviews from people who have used the product. Most of these reviews are positive and confirm the claims made by Nature Made regarding this supplement.


5) CholestOff Complete Warnings and Precautions

The following precautions must be kept in mind if you are thinking of using CholestOff for the first time:

  • The supplement is not safe for use by lactating and pregnant women
  • It is not meant to be used by children
  • Do not use CholestOff if you have an allergy to pine trees or any other ingredient of this product
  • If you are currently using any medication, particularly the ones to lower your cholesterol levels, consider consulting with a doctor before using CholestOff
  • Do not combine CholestOff with any other medication before seeking expert advice. Such combinations may often result in undesirable effects, such as reduced efficacy of the supplement, diminished drug efficacy, or impaired absorption of both
Where to Buy?

6) Where to Buy CholestOff Complete

CholestOff is available through different platforms, such as:

  • The company’s official website (naturemade.com)
  • Amazon
  • Walmart
  • iHerb
  • Walgreens
  • CVS
  • eBay

7) CholestOff Complete Cost

One pack of CholestOff containing 120 soft gel capsules is priced at $42.69 on the official website of Nature Made. You can avail of a 10% discount by subscribing to the auto-shipping feature and getting the bottle at a reduced price of $38.42. The official website also features a location finder that helps clients find the nearest stores that sell CholestOff in person.

Keep in mind that the prices for CholestOff may vary depending on where you purchase it from.


8) CholestOff Complete Directions

CholestOff is available in the form of oral capsules that are convenient to take on a daily basis. The recommended serving for this supplement is two capsules twice a day which provides a user with an 1800 mg dosage in total. The best time to take this nutritional supplement is just before meals, ideally with a half-hour gap in between. Use a full glass of water to swallow the pills whole and consume them frequently to experience faster results.

Bottom Line

9) Our Bottom Line

CholestOff seems like a legit product to reduce cholesterol levels in the blood. It is supported by multiple positive reviews and is priced affordably so more people can access it. However, it is not a suitable supplement for everyone, especially pregnant and breastfeeding women. Moreover, the company has warned not to use it as an alternative to any cholesterol-lowering pharmaceutical drug. The results obtained from using CholestOff can vary in different users; hence, consulting a doctor before adding it to your daily routine is recommended.

3.5/5 - (21 votes)
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I took Cholest Off for a solid year and my cholesterol results did not improve they got worse.

Title for your comment
Cholest off did not work for me
Have you tried this product?

Is CholestOff a Statin? I asked my doctor and she said it is, buy I’m not finding that point in online searches.

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Is CholestOff a Statin
Have you tried this product?

I bought this at the recommendation of a friend who had been using it for several months. I feel very good and so far there are no side effects. We’ll see what the tests say in a couple of weeks.


CholestOff Complete is offered by one of the most trustable manufacturers. This is why I decided to try it in order to lower my cholesterol which was (according to my last test results) slightly elevated. In a few months my cholesterol was in its normal limits again. I will continue to use this product because it really works for me.