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Imipramine Review – 4 Reasons To Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Ingredients | Cost | Bottom Line

Imipramine is marketed as a type of antidepressant. It is claimed to be a medication that can help regulate mood and the levels of chemicals in the brain.

It is often offered as a form of medication for severe types of depression that haven’t responded well to other forms of treatment according to information online. This particular medication has been around since 1950.

This particular medication is offered by many different names out there on the market. That is because Imipramine is a generic formula. Some of the name brand products you will find out there include Doxepin and Amitriptyline.

There are many different manufacturers of this particular form of medication due to the high demand in our society.

You can only get Imipramine through a prescription by a doctor. It is often given in conjunction with medical supervision and therapy. This is stated to be a compelling form of antidepressant.

It is strongly discouraged for anyone to take it when it hasn’t been specifically prescribed for them. Still, this product continues to be sold illegally on the black market.

Many doctors offer free samples of Imipramine to get a good indication of how a patient will respond to it before they prescribe it. Typically, this form of medication is tried after other efforts with various types of medication have failed to offer substantial benefits for the patient.


1) Imipramine Ingredients

Imipramine includes the following ingredients: Imipramine Hydrochloride.

2) What Does Imipramine Do?

According to the online information that shows people have been able to successfully have a high quality of life with depression and panic disorders when they use this medication, there have been clinical studies over the years.

However, information isn’t offered about what studies have been done, how many people were successful with it, or how long they took the drugs.

In addition to being offered as a form of medication for severe depression and panic disorders, Imipramine is also promoted to assist with a lack of control over urinating, called Enuresis.

It is stated to work by helping to get the balance of chemicals regulated in the brain. There is no additional information offered, though, about exactly how this is to be accomplished.

The dose of this medication can be challenging to get correct, so close medical supervision is required. If a patient is in the hospital, the typical amount is 25 mg 3 times per day, but up to 125 mg is given per day.

For outpatient use, the dose is to start with 25 mg per day and then increase it to no more than 200 mg per day if necessary. For children, the recommended amount of Imipramine is no more than 10 mg per day. Failure to follow dosage guidelines carefully may result in accidental overdose.

Many listed side effects have been associated with the use of Imipramine.

Such side effects include dizziness, headaches, anxiety, drowsiness, insomnia, heartbeat changes, blurred vision, changes in food taste, and sensitivity to sunlight.

If severe symptoms such as swelling, trouble breathing, or lethargy occur, immediate medical attention is advised. It is never a good idea to take Imipramine when you are pregnant or nursing.

Talk to your doctor about taking it with other forms of prescription or over the counter medications.


3) Imipramine Cost

Imipramine is less expensive than the name brands of this same medication. Still, it can be pricey when someone has to take it regularly.

The cost of it depends on any insurance coverage that may exist. Most insurance companies will cover this particular medication. Any co-pays or deductibles that are part of the health insurance plan or prescription plan will apply.

Many offers are out there for low-cost medications too for those that can’t afford them.

If you have prescribed Imipramine, but you can’t afford it, let your doctor know. They may be able to refer you to a program that would help you to be able to afford it.

Many of them are sliding scale fees, so you will only pay a fraction of the regular cost.

Bottom Line

4) The Bottom Line – “Does it Work?”

We are still in the testing phase with Imipramine from Novartis and will update with our results very soon. But until then, please share your personal experience below with us and support our entire community.

3.3/5 - (3 votes)
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