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CalmTrex Review – 8 Things You Should Consider

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Ingredients | Adverse Effects | Price | Suggested Use | Final Thoughts

CalmTrex is advertised as a cutting-edge supplement that may effectively relieve common symptoms of depression and anxiety, lower stress, enhance attention span and concentration skills, and generally improve cognitive function.

It is one of the numerous products offered by the American manufacturer Stop Aging Now that has been present in the healthcare products market for almost two decades and has an excellent reputation among consumers.

This article discusses CalmTrex’s ingredients, uses, potential benefits, and side effects. If you consider taking CalmTrex to support relaxation or improve mood, read this article to find out more.


1) What is CalmTrex?

CalmTrex is a herbal formula designed to help reduce stress-related food cravings, boost energy, and support relaxation.

The formula is primarily based on herbal extracts, of which the most crucial is Zembrin, a patented extract of the herb Sceletium Tortuosum, researched for its believed benefits on the nervous system and brain.

CalmTrex is believed to relieve stress and anxiety and promote overall mood elevation effectively.


2) Details on CalmTrex Ingredients and Uses

CalmTrex contains

  • Vitamin B6
  • Vitamin B12
  • Ashwagandha Extract
  • Lemon Balm Extract
  • Sceletium tortuosum Extract

Zembrin is the main active compound featured in this supplement. This is a standardized herbal extract of Sceletium tortuosum that has been traditionally used as a medicinal plant in South Africa to relieve fatigue, elevate mood, and reduce depression and anxiety.

Zembrin is believed to act in two different ways, resulting in PDE4 inhibition and 5-HT reuptake, boosting Serotonin levels, making this compound such a potent natural stress reliever.

Existing clinical trials seem to support the compound’s action on the neural circuits involved in processing emotions, particularly in managing anxiety and stress.

3) CalmTrex Benefits & Results

CalmTrex can help

  • Reduce stress-related food cravings
  • Improve mood
  • Improve cognitive function
  • Boost energy levels
  • Support healthy sleep
  • Improve relaxation
  • Relieve relief from stress and anxiety
Adverse Effects

4) Potential CalmTrex Adverse Effects

Some ingredients in CalmTrex, like Ashwagandha, may cause nausea, stomach upset, and diarrhea.

Where to Buy?

5) Where to Buy CalmTrex?

You can buy CalmTrex from the manufacturer’s website.


6) CalmTrex Price

A month’s supply of CalmTrex costs $32.99

Suggested Use

7) Suggested Use

Take two capsules of CalmTrex daily with food, or as directed by your physician.

Final Thoughts

8) Final Thoughts on CalmTrex

CalmTrex is a herbal formula designed to help reduce stress-related food cravings, boost energy, and support relaxation, and is marketed as a potent natural antidepressant suitable for those who seek a safer alternative to traditional medication.

If you are looking for an effective herbal remedy to help you combat anxiety, relax, or reduce stress, CalmTrex can provide fast-acting relief; However, we recommend that you consult your physician if you have any preexisting medical conditions.

4.5/5 - (6 votes)
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Fiona D.

CalmTrex is one of the best natural antidepressants I have tried. After quitting prescription drugs (due to the numerous side effects I was experiencing) I tried different brands of herbal remedies and dietary supplements to alleviate my depression. And I stopped to this one because it is very effective in a small period of time. If I miss my daily dose I immediately feel sad and get annoyed very fast. CalmTrex has helped me to become a better person!


I like this herbal remedy because it works very fast and help me be less aggressive and feel happier. I have also noticed an improvement in my sleeping patterns lately.


I’ve only been taking it for 4 days and I feel great! I sleep great and have a sharper mind.


Are all the ingredients non-stop or organic? I am allergic to corn….and anything they make with corn. Thank you for taking time to answer.my question.

Iulian (Editor)
Reply to  Nancy


CalmTrex ingredients are not organic, and it contains milk (Ashwagandha is prepared following Ayurvedic tradition resulting in trace quantities of milk remaining in the product). However, it doesn’t contain any of the more common allergens like egg, fish, shellfish, tree nuts, wheat, soy, and peanuts.

Richard Clark

How do I order Calm Trex, I have used it, and can not find a place to get replacements, would you please help me out.

Iulian (Editor)
Reply to  Richard Clark

CalmTrex is available online on Stop Aging Now official store. They even offer some deals: 1 bottle (one month supply) for $29.95, 3 bottles for $80.85, and 6 bottles for $149,70.