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PRO-15 Review – 7 Things You May Not Know

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Summary | Nutrition Info | Health Benefits | Contraindications | Cost | Dosing | Final Thoughts

The number one selling probiotic supplement on Amazon, PRO-15, is a dietary supplement meant to restore the health of your digestive system by replenishing the natural microbiome within the gastro-intestinal tract. Manufactured by Hyperbiotics, an L.A. based American Domestic Corporation, this product’s efficiency is guaranteed by their patented BIO-tract technology. BIO-tract claims to help preserve the bacteria for longer periods of time, and protect them from stomach acid. This makes it possible for the probiotics to reach areas in the digestive system where they are most needed.

From birth, our bodies develop a microbiome of their own. Microbiome is best defined as the community of microorganisms that are found both within and on our bodies. These bacteria are essential to our overall health. However, the broad-spectrum antibiotics often used in modern medicine combined with the current lifestyle in terms of diet choices, as well as environmental conditions people have to cope with slowly diminish the number of beneficial bacteria, particularly those that reside in the GI (gastro-intestinal) tract. The role of PRO-15 is to provide a productive and efficient means to regain gut microbes, manufactured in a way to suit both maintenance use, may help to support weight management, mood and energy levels, and related digestive issues.

This is one of the most productive probiotics available on the market, with proven tests guaranteeing the PRO-15 complex is actually filled with living microorganisms. The easy-to-swallow BIO-tract pearls make for a positive maintenance use and aiding in digestion.


1) What is PRO-15?

Enjoying one of the best reputations on Amazon, the PRO-15 blend has helped thousands of people regain the health of their digestive flora. The major concern behind negative customer experience pertains to the product’s lack of effectiveness or the persistence of effects it was designed to combat. Nonetheless, probiotics work in a manner that is alike to certain vitamins and minerals – they are stored by the body.

Sometimes, the effect is not instant and it may take a few months to notice consistent improvement, some users may experience mild side effects such as initial bloating, gas or constipation as a result of detoxification. After a few weeks, once the intestinal flora is remodeled, previous symptoms, as well as any other that were brought about by the pearl may begin to subside.

The 15 different strains available in PRO-15, acombined with prebiotics are another benefit for this product. Prebiotics act as food to keep probiotic bacteria alive and thriving. Thus, the Hyperbiotics formula is designed to account for diversity, resistance and potency. The recommended daily dosage is one pearl tablet per day for daily maintenance. For intense repair, they recommend 3 pearl tablets per day is the ideal dosage.

Nutrition Info

2) Ingredients of PRO-15

PRO-15 contains the following ingredients per serving: Proprietary Probiotic Blend, 5 billion Colony Forming Units (CFU): L.plantarum, L. fermentum, L. acidophilus, B. infantis, L. casei, B. longum, L. rhamnosus, B. lactis, L. reuteri, L. salivarus, L. paracasei, L. gasseri, S. termophilus, B. bifidum, B. breve; Prebiotic Fructooligosaccharides (FOS) 25 mg. Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Pectin, Stearic Acid, Sodium Carbonate, Guar Gum, Turmenic (color). May contain trace amounts of the milk protein casein from the fermentation process. PRO-15 is lactose free.

Health Benefits

3) PRO-15 Health Benefits

  • 15 strains of probiotics that bring together 5 billion colony forming units.
  • Strong shelf-life and no refrigeration necessary.
  • Easy to swallow pearl-shaped tablets manufactured with the BIO-tract technology that protects strains which are usually destroyed by stomach acid.


4) PRO-15 Warnings and Precautions

  • Might cause initial bloating, gas or constipation.
  • No free trial period available.
  • Moderate pricing.


5) PRO-15 Cost

The PRO-15 price is moderately low. Given the wide variations in the suggested dose, one bottle can last between 20 days and 2 months. Although the initial price was almost two times higher, at the moment of this review, you can purchase a bottle for the price of $24.


6) PRO-15 Serving Size

PRO-15 comes at a moderate price. Taking into account the above mentioned, as well as the fact that these pearls are gluten free, non-GMO and yeast free, contains no dairy, soy, nuts, preservatives, sugars, artificial flavors or colors, PRO-15 offers great value.

Final Thoughts

7) Final Thoughts on PRO-15

The PRO-15 compound is an intelligently designed product with special attention paid to the quality and quantity of the microorganisms that it contains.

Devising an easy to swallow pearl-shaped pill, the manufacturer of PRO-15 also focused on whether the beneficial microbiota reaches the right gastro-intestinal areas, thus managing to come up with a blend that is delivered in an efficient and effective way. The fact that refrigeration for storing is not necessary comes as an added benefit.

In perspective, PRO-15 is created using a patented technology designed for efficiency and effectiveness. It is free from many of the common allergens and is a certified vegetarian product.

4/5 - (1 vote)
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