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NuSera Review – Is it Effective?

By Dr. Usmarah Hussain

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Overview | What's Inside? | Pros & Cons | Cost | Where to Buy? | Suggested Use | Conclusion

NuSera is a dietary supplement that aims to provide people with stress relief during critical moments of their life. This great-tasting, chocolate-flavored product induced natural relaxation by altering the brain chemistry without any unwanted side effects. Ideal for people who frequently tackle stressful situations in life, can this product be the change they need? This in-depth NuSera review will explain all bits about the supplement and help you decide whether it is worthy of being a part of your daily life.


1) Quick Overview

The fast-paced life of today brings many troubles and stressors on a day-to-day basis. While many people successfully keep things rolling while keeping their stress levels under control, others may struggle to get anything done. For such people, Metagenics has introduced an innovative supplement called NuSera. Based on a single patented ingredient called Lactium, this unique formula combats stress by regulating the GABA inhibitory action in the brain and promoting a healthier stress response. Clinical studies have greatly backed up this product’s ability to fight stress which can make a healthy lifestyle possible.

NuSera is currently available at moderately-high prices. It comes in chewable forms with a delicious chocolate flavor that can be easily and pleasantly incorporated into daily life. The formula is free from GMOs and gluten; however, it may not be suitable for vegetarians due to its milk-based ingredients.

2) The Company Behind NuSera

The company manufacturing NuSera is based in the U.S. and is called Metagenics. The company was established in Aliso Viejo, California, in 1983 and deals in nutritional supplements, lifestyle programs, and medical foods to help people achieve a sound state of health. This company states that they regard quality like no other company and devotes significant resources and personnel to test each ingredient’s safety. Each test batch of the formula developed under its label is checked in different key stages of development as well.

This business first started out in the United States but now has international status and has opened offices in New Zealand, the Netherlands, Australia, Belgium, and Canada. In 2009, Metagenics was acquired by Alticor Inc. as a subsidiary and currently employs over a thousand people worldwide with a revenue of approximately $330 million per year.

What’s Inside?

3) What’s Inside NuSera?

NuSera is a single-ingredient product that includes a patented formula called Lactium. This formula has been developed by top scientists after years of experience through which they learned how to reproduce a baby’s digestive mechanism through an innovative process. The expert team used trypsin, a well-known naturally-existing digestive enzyme in the milk, to extract one of its protein hydrolysates that contains a bioactive peptide called alpha casozepine. This peptide, now known as Lactium, has known to have many benefits, such as counteracting loss of appetite and libido, sleep issues, memory problems, concentration, and mood swings.

Experts also found that Lactium possesses a selective affinity for specific receptors in the brain called GABA receptors. Moreover, it can also upregulate the activity of gamma-aminobutyric acid (GABA), a natural neurotransmitter that possesses an inhibitory action and can relax the mind to counteract anxiety and stress while inducing relaxation. However, the product is different because it can get the job done without exposing the brain to any risk of addiction, like benzodiazepines or other pharmaceutical drugs.

4) Does NuSera Work?

NuSera is different from other stress-relief products in a way that it relies on a single ingredient to get the job done. Instead of offering a blend of multiple ingredients, clients can rely on Lactium, a patented formula with lots of evidence to back its stress-relief formula. The research supporting this ingredient’s ability to lower stress and anxiety seems promising. Moreover, the single-ingredient formula helps clients do their own research without facing any difficulties or challenges. Furthermore, they can know for sure exactly what they are ingesting when they decide to take NuSera, in contrast to other supplements with lengthy formulations that may come with many hidden ingredients.

Because of Lactium’s direct effects on the brain, it can lead to instant stress-busting effects by regulating the core neurotransmitters responsible for inducing a state of calm. Moreover, because it regulates the body’s stress response, it may possibly help it learn how to respond better to any stressors in the future. The gluten-free, non-GMO product can cater to people with stressful lives and help them deal with their issues without facing too much mental tension. Customer reviews regarding NuSera are readily available on the internet, most of which show the product in a good light, depicting how it has helped them relax and unwind.

Pros & Cons

5) NuSera: Pros and Cons

Mentioned below are the pros and cons of choosing NuSera as a natural stress-relief formula:


  • This supplement comes in the form of chewable tablets, which makes it easier to use whenever and wherever needed
  • It has a pleasant chocolate-flavored taste
  • It does not require day-to-day use and can be consumed during a stressful period on a need basis
  • The product has many online reviews with positive comments


  • NuSuera is not suitable for vegetarian use
  • The main ingredient is not recommended for use by pregnant or nursing women
  • The price of this formula may be a bit high for some users
Where to Buy?

6) Where to Buy NuSera

Visit Metagenics.com to place an order for NuSera from the company’s official website. This platform is the best place to get your hands on authentic products without any risk of scams. Alternatively, you may consider ordering from Amazon.


7) How Much Does NuSera Cost?

NuSera is available in the form of oral pills enclosed in good-quality plastic bottles. Each bottle contains 30 chewable tablets and comes at a cost of $43.25. While the supplement may seem a bit on the pricier side compared to other alternatives, customers can avail of a 10% discount from the company by subscribing to the auto-shipping program, which brings down the per-bottle cost to $38.93. This subscription also allows users to save on shipping costs.

Suggested Use

8) Suggested Use

Take one tablet, with a maximum of four tablets per day, whenever you feel overstressed.


9) Conclusion

NuSera is a dietary health product created to provide people with a fast-acting, effective way of stress relief during all crucial moments of their life. The company responsible for developing it has 30 years of experience in the supplement business and has an international status, which adds to the overall credibility. The formula is simple and based on one evidence-based ingredient with no complex ingredient mixtures and blends. NuSera is easily available online through the manufacturer’s official company at moderate prices that most people can easily afford. Overall, for people with stress-relieving issues, NuSera can be worth a try.

2.8/5 - (9 votes)
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Was great, until last night

I have been taking this for a few years for extreme insomnia. I opened a fresh bottle last night and took one. About 30 min later I had the worst stomachache. Has the formula recently changed? Is their any gluten in it?

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Have you tried this product?

Not only does this formula help with stress and provides calm, but it also provides a good night’s sleep as well.

Kathy S

I love that this formula can be used just when it’s needed, every time I feel a tense situation uprising I use a tablet and then I have the calm needed to address it.

Sharon Berliner

I am sensitive to casein. Is there enough casein In NuSera that it may cause problems?

Iulian (Editor)

Hi Sharon,

The list of ingredients we have is the list offered by the manufacturer on their official website. According to this list, NuSera does not contain casein.