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Nature Made Ubiquinol CoQ10 Review – Is it Effective?

By Sasha de Beausset Aparicio, MSc

Reviewed by Rebecca Williams, MD, MA, MB, BChir

Last Updated:

Evidence Based | Overview | What's Inside? | Pros & Cons | Precautions | Directions | Conclusion

Ubiquinol CoQ10 is the reduced form of Coenzyme Q10 and is the newest member of Nature Made’s product line.

Ubiquinol CoQ10 has been widely studied for the role it plays in helping to maintain heart function, increase intracellular energy, boost the immune system, and helps reduce oxidative stress. CoQ10 can also support brain health.

It is designed and manufactured by a renowned company Nature Made  who claims that their product contains the reduced form of CoQ10 and is entirely free from soy, GMOs and other artificial ingredients. The recommended dose of this product is one soft gel per day, and each packet contains 30 soft gels means a full month supply of cardiac protection and antioxidant support.


1) Quick Overview

Coenzyme Q10 (CoQ10) is a fat-soluble compound produced naturally in our bodies. Found in nearly every cell in the body, CoQ10 is concentrated in the vital organs that require the most energy such as the muscles, heart, liver, and kidneys. CoQ10 is concentrated in these organs because it is essential to the process of producing cellular energy from the food you eat.

The natural production of Ubiquinol decrease with age; however certain genetical and environmental factors also influence its levels. The concentration of CoQ10 rapidly falls in statin (drugs that reduce the production of cholesterol) users due to the fact that besides reducing cholesterol levels, statins also inhibit the synthesis of Ubiquinol. Therefore regulating its normal levels are essential to replenish its lost levels and to restore optimal functions. Supplementation may help maintain these lowered levels, and aid in reducing adverse disease symptoms.

Nature Made is a large manufacturer of nutritional supplements, with a reputation for high quality, affordable products. Their Ubiquinol product is no different. This product contains pure Ubiquinol with higher absorption formula that helps restore and maintain optimal levels of CoQ10. Maintaining healthy levels of CoQ10 will benefit not only oxygen utilization but also energy production. It has also been shown to be effective in reducing the deterioration of the brain cells. Recent studies have shown a reduction in oxidative stress, disease prevention and aid in long-term brain preservation.

What’s Inside?

2) What’s Inside Ubiquinol CoQ10?

Ubiquinol CoQ10 contains the following ingredients: Ubiquinol (reduced form of CoQ10) 100 mg.

Pros & Cons

3) Ubiquinol CoQ10: Pros and Cons

  • Supports optimal heart health, increase natural cellular energy production and helps prevent damage in the body caused by oxidative stress.
  • Replenishes CoQ10 blood levels depleted by several cholesterol lowering medicines.
  • Boost energy production thus helps reduce post workout fatigue.

4) Precautions of Ubiquinol CoQ10 Use

  • May cause GI upsets like heart burn, stomach irritation, bloating and diarrhea. Some consumers also complain of occasional insomnia (sleeplessness).

5) Ubiquinol CoQ10 Directions

Ubiquinol CoQ10 appears to be safe, with no reported side effects in clinical studies, except occasional gastrointestinal upsets. CoQ10 may adversely interact with some blood pressure and blood-thinning medications, and some over-the-counter pain relievers.


6) Conclusion

Ubiquinol CoQ10 provides an excellent option of coenzyme Q10, for individuals looking for an extra strength dosage. This supplement packs 200 mg (double the standard dose) into each serving. It promotes energy production, reduces fatigue and protects the heart muscles from oxidative stress and damage caused by free radicals. The supplement is manufactured responsibly and gets high user ratings on Amazon. Additionally, the product contains zero fillers, binders, or artificial ingredients.

4/5 - (2 votes)
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