Treximet Review – 8 Reasons Why
By Sasha de Beausset Aparicio, MSc, Rebecca Williams, MD, MA, MB, BChir (Expert Reviewer)
Rebecca Williams studied medicine at Cambridge University where she also obtained a degree in Experimental Psychology. A widely known General Practitioner in London, Rebecca also served in Community Pediatrics, and has published research in the field of complementary and alternative medicine.
Rebecca relocated to Johannesburg, South Africa where she has been able to pursue holistic community healthcare by developing a community health training program which she has taught in Mozambique, Zambia, Uganda and Nepal.
Some of Rebecca’s published research can be viewed on Researchgate.
Treximet is a product designed to mediate vasoconstriction, vasculature of human dura-mater and inhibit the synthesis of inflammatory mediators in order to obtain relief of migraine headache.
The manufacturer is the international worldwide renowned pharmaceutical company GlaxoSmithKline (headquartered in UK) which produces a wide range of medicinal products which treat major diseases like diabetes, cardiovascular, mental health, asthma, infections and digestive conditions.
This supplement is advertised as a migraine treatment based on 2 active ingredients, sumatriptan and naproxen which contribute to the relief of migraine through pharmacologically different mechanisms of action.Treximet has been the subject of double-blind randomized trials and has proven effective in reducing headache severity from moderate or severe to mild or no pain.
Please note that Treximet is a form of prescription medication and should only be used under strict doctor’s orders.
1) What is Treximet?
Treximet is a prescription drug product designed to fight acute migraine attacks in adults.
Sumatriptan is one of the two active ingredients in this product which mediates vasoconstriction and has been proven, through clinical trials on animals, to activate the trigeminal nerve innervating cranial blood vessels. These tests conclusions are that Sumatriptan may contribute to the antimigrainous effect in humans.
Naproxen sodium is a Nonsteroidal Anti-inflammatory Drug (or NSAID) with known analgesic properties. Although its exact mechanism of action is not fully understood, researchers believe it works by inhibiting the synthesis of inflammatory mediators, which may cause migraine pain.
There are several severe side-effects mentioned by the manufacturer, most important being cardiovascular conditions related (may increase risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal), gastrointestinal related (the NSAID ingredient causes increased risk of serious gastrointestinal adverse events like ulceration, bleeding and perforation of the stomach or intestines, which can be fatal).
2) Treximet Ingredients
Treximet contains the following ingredients: sumatriptan succinate, naproxen sodium, croscarmellose sodium, dextrose monohydrate, dibasic calcium phosphate, FD&C Blue No. 2, lecithin, magnesium stearate, maltodextrin, microcrystalline cellulose, povidone, sodium bicarbonate, sodium carboxymethylcellulose, talc, and titanium dioxide.
3) Does Treximet Work?
Treximet is a type of prescription medication categorized as NSAID (nonsteroidal anti-inflammatory drug). This product is primarily used to treat chronic pain caused by various forms of arthritis. However, it is also believed to be effective in reducing inflammation.
Treximet is available in liquid form (commonly prescribed for children) or pill form. The dose will depend on the type of arthritis, the severity of pain and the depth of the problem. A doctor will recommend the dose and the product should be taken only under close medical supervision.
Please note that this is a slow-acting drug and it may take up to 4 weeks to feel the first results. However, the manufacturer claims that most patients should feel some relief within two weeks.
Women who are pregnant or nursing shouldn’t use it. Individuals who are allergic to aspirin shouldn’t use this form of medication. Those with kidney or liver problems shouldn’t use this product either. It is not advised to use Treximet in association with herbal remedies or other forms of natural supplements. There may be interactions between the ingredients found in this formula and various herbal extracts or amino acids.
Various side effects have been reported with the use of Treximet. They include dizziness, drowsiness, irritability, nausea or vomiting, insomnia, dry mouth, headaches, sores that form in the mouth, ringing in the ears, and tingling sensations in the arms or legs. Serious side effects that should be reported to the doctor immediately include hearing loss, dark colored urine, abdominal pain, swelling and changes in heart beat.
4) Treximet Benefits & Results
- Clinically researched product
- Reputable, international manufacturing company
- Approved by the FDA.
5) Treximet Product Warnings
- Large number of severe side-effects (like in most cases of prescription medication)
- Few consumer reviews available
- Long list of precautions.
6) Treximet Price
Treximet is a form of prescription medication and an expensive product. There is a nonprescription form of Treximet (Aleve) available on the market, but it may be less effective than the original product. Most of the insurance plans and prescription cards will cover the cost of this medication.
7) Treximet Serving Size
The recommended dose of Treximet is one tablet whenever migraine appears.
8) Bottom Line – Does It Really Work?
Treximet is a medically researched prescription anti-migraine drug manufactured by GlaxoSmithKline, an international leader in medical industry.
The formula is based on 2 active ingredients and underwent clinical trials with good results regarding its effectiveness. It is a product approved by the FDA but has many serious (some of which can even prove fatal) side-effects and drug interactions warnings.
The manufacturer recommends that consumers use Treximet under a healthcare professional’s supervision and take immediate measures in case of any listed side effect occurs. Special precautions are issued for pregnant women, as test results on animals have revealed decrease of fetal bodyweight, increase of embryo fetal death and malformation occurrence.
Customers Questions and Answers with Treximet
- Recent:
Treximet includes the following ingredients: sumatriptan, naproxen sodium, croscarmellose sodium, dextrose monohydrate, dibasic calcium phosphate, FD&C Blue No. 2, lecithin, magnesium stearate, maltodextrin, microcrystalline cellulose, povidone, sodium bicarbonate, sodium carboxymethylcellulose, talc, and titanium dioxide.
Treximet is a form of prescription medication meant to assist with in relieving various types of pain, swelling, and stiff joints that may be caused by various types of arthritis. The product belongs to the NSAID (nonsteroidal anti-inflammatory drug) category and is a slow-acting drug; it may take up to 4 weeks for the first results to appear. The company behind this product is GlaxoSmithKline.
Many users give high praise to this medication and support its claim to be effective in easing the pain associated with arthritis. However, the only one entitled to decide if this drug is good for you or not is your doctor.
It is important to understand that Treximet is a form of prescription medication with potentially dangerous side effects and it should not be taken without a doctor's written consent.
When I start feeling my migraine headache I take my pill Treximet and 15 minutes later my pain is gone.
I only used half a pill and wow it was wonderful. It also relieved the tension and strain that I always hold in my neck, back and shoulders.
I have been suffering from headaches and migraines for almost four years. I have tried butalbital, midrin, imitrex and now treximet. By far it is the best. It works quickly and much fewer side effects than the imitrex. It did leave me feeling sleepy, but that is much better than the pain anyday.